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Support for Barker hypothesis upheld in rat model of maternal undernutrition during the preimplantation period: application of integrated 'random effects' statistical model

Support for Barker hypothesis upheld in rat model of maternal undernutrition during the preimplantation period: application of integrated 'random effects' statistical model
Support for Barker hypothesis upheld in rat model of maternal undernutrition during the preimplantation period: application of integrated 'random effects' statistical model
In response to a recent paper published in Reproductive BioMedicine Online by Walters and Edwards (2003), this study reports the application of a random effects regression analysis for evaluation of integrated data involving maternal and embryo/offspring components. Using this method, it is possible to confirm the conclusions of an earlier study that rat maternal undernutrition during the preimplantation period results in blastocyst cell number reduction and postnatal outcomes, including altered growth rates and elevated blood pressure.
1472-6483
574-576
Kwong, W.Y.
8c0db2b8-e2c0-46ea-b5d6-4ad632938062
Osmond, C.
2677bf85-494f-4a78-adf8-580e1b8acb81
Fleming, T.P.
2abf761a-e5a1-4fa7-a2c8-12e32d5d4c03
Kwong, W.Y.
8c0db2b8-e2c0-46ea-b5d6-4ad632938062
Osmond, C.
2677bf85-494f-4a78-adf8-580e1b8acb81
Fleming, T.P.
2abf761a-e5a1-4fa7-a2c8-12e32d5d4c03

Kwong, W.Y., Osmond, C. and Fleming, T.P. (2004) Support for Barker hypothesis upheld in rat model of maternal undernutrition during the preimplantation period: application of integrated 'random effects' statistical model. Reproductive BioMedicine Online, 8 (5), 574-576.

Record type: Article

Abstract

In response to a recent paper published in Reproductive BioMedicine Online by Walters and Edwards (2003), this study reports the application of a random effects regression analysis for evaluation of integrated data involving maternal and embryo/offspring components. Using this method, it is possible to confirm the conclusions of an earlier study that rat maternal undernutrition during the preimplantation period results in blastocyst cell number reduction and postnatal outcomes, including altered growth rates and elevated blood pressure.

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More information

Published date: May 2004

Identifiers

Local EPrints ID: 25737
URI: http://eprints.soton.ac.uk/id/eprint/25737
ISSN: 1472-6483
PURE UUID: 07eb7608-4112-449a-89b1-bca96011c249
ORCID for C. Osmond: ORCID iD orcid.org/0000-0002-9054-4655

Catalogue record

Date deposited: 10 Apr 2006
Last modified: 23 Jul 2022 01:39

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Contributors

Author: W.Y. Kwong
Author: C. Osmond ORCID iD
Author: T.P. Fleming

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