Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics
Paisey, J.R., Betts, T., Allen, S., Morgan, J.M. and Roberts, P.R. (2004) Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics. Europace, 6, (1), 21-24. (doi:10.1016/j.eupc.2003.09.005).
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Description/Abstract
Aims
To investigate the correlation between body weight and defibrillation threshold (DFT) for transvenous lead systems using a porcine model.
Methods and results
Twenty-eight pigs were anaesthetised and DFTs assessed in single and dual coil configurations using a four-reversal binary search method. DFT was correlated with body weight in the RV → Can and RV → SVC + Can configurations. A Pearson correlation coefficient and a two-sided p-value were calculated. A positive correlation exists between body weight and DFT in RV → Can (, ) and RV → SVC + Can (, ).
Conclusion
There is a significant correlation between body weight and DFT in swine. This tends to be greater in the two-electrode than in the three-electrode configuration. With these and previous human observations, one may predict a higher DFT in heavy individuals and make appropriate procedural adjustments.
| Item Type: | Article |
|---|---|
| Additional Information: | Review |
| ISSNs: | 1099-5129 (print) |
| Related URLs: | |
| Keywords: | implantable cardioverter defibrillator, defibrillation threshold, ventricular arrhythmia, fibrillation, body weight |
| Subjects: | R Medicine > R Medicine (General) Q Science > QP Physiology |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease |
| Item ID: | 25871 |
| Date Deposited: | 21 Apr 2006 |
| Last Modified: | 01 Jun 2011 08:48 |
| Contributors: | Paisey, J.R. (Author) Betts, T. (Author) Allen, S. (Author) Morgan, J.M. (Author) Roberts, P.R. (Author) |
| Date: | 2004 |
| Additional Information: | Review |
| Status: | Published |
| Contact Email Address: | J.M.Morgan@soton.ac.uk |
| URI: | http://eprints.soton.ac.uk/id/eprint/25871 |
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