Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics


Paisey, J.R., Betts, T., Allen, S., Morgan, J.M. and Roberts, P.R. (2004) Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics. Europace, 6, (1), 21-24. (doi:10.1016/j.eupc.2003.09.005).

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Description/Abstract

Aims

To investigate the correlation between body weight and defibrillation threshold (DFT) for transvenous lead systems using a porcine model.

Methods and results

Twenty-eight pigs were anaesthetised and DFTs assessed in single and dual coil configurations using a four-reversal binary search method. DFT was correlated with body weight in the RV → Can and RV → SVC + Can configurations. A Pearson correlation coefficient and a two-sided p-value were calculated. A positive correlation exists between body weight and DFT in RV → Can (, ) and RV → SVC + Can (, ).

Conclusion

There is a significant correlation between body weight and DFT in swine. This tends to be greater in the two-electrode than in the three-electrode configuration. With these and previous human observations, one may predict a higher DFT in heavy individuals and make appropriate procedural adjustments.

Item Type: Article
Additional Information: Review
ISSNs: 1099-5129 (print)
Related URLs:
Keywords: implantable cardioverter defibrillator, defibrillation threshold, ventricular arrhythmia, fibrillation, body weight
Subjects: R Medicine > R Medicine (General)
Q Science > QP Physiology
Divisions: University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
ePrint ID: 25871
Date Deposited: 21 Apr 2006
Last Modified: 27 Mar 2014 18:14
URI: http://eprints.soton.ac.uk/id/eprint/25871

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