Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics

Paisey, J.R., Betts, T., Allen, S., Morgan, J.M. and Roberts, P.R. (2004) Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics. Europace, 6 (1), 21-24. (doi:10.1016/j.eupc.2003.09.005).

Abstract

Aims
To investigate the correlation between body weight and defibrillation threshold (DFT) for transvenous lead systems using a porcine model.
Methods and results
Twenty-eight pigs were anaesthetised and DFTs assessed in single and dual coil configurations using a four-reversal binary search method. DFT was correlated with body weight in the RV ? Can and RV ? SVC + Can configurations. A Pearson correlation coefficient and a two-sided p-value were calculated. A positive correlation exists between body weight and DFT in RV ? Can (, ) and RV ? SVC + Can (, ).
Conclusion
There is a significant correlation between body weight and DFT in swine. This tends to be greater in the two-electrode than in the three-electrode configuration. With these and previous human observations, one may predict a higher DFT in heavy individuals and make appropriate procedural adjustments.

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