Scouting Enzyme Behavior
Matsumaru, N., Colombano, S. and Zauner, K.-P. (2002) Scouting Enzyme Behavior. In, Fogel, D. B., El-Sharkawi, M. A., Yao, X., Greenwood, G., Iba, H., Marrow, P. and Shackleton, M. (eds.) Proceedings of the 2002 World Congress on Computational Intelligence, May 12-17 Honolulu, Hawaii. , IEEE, Piscataway, NJ, CEC19-24.
Download
![[img]](http://eprints.soton.ac.uk/style/images/fileicons/application_pdf.png) |
PDF
Download (548Kb) |
Description/Abstract
Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises.
| Item Type: | Book Section |
|---|---|
| ISBNs: | 0780372786 |
| Keywords: | scientific discovery, biochemistry, systems biology, malate dehydrogenase, autonomous experimentation, evolution, surprise |
| Divisions: | Faculty of Physical and Applied Science > Electronics and Computer Science > Agents, Interactions & Complexity |
| Item ID: | 259133 |
| Date Deposited: | 12 Mar 2004 |
| Last Modified: | 06 Mar 2012 17:13 |
| Contributors: | Matsumaru, N. (Author) Colombano, S. (Author) Zauner, K.-P. (Author) Fogel, D. B. (Editor) El-Sharkawi, M. A. (Editor) Yao, X. (Editor) Greenwood, G. (Editor) Iba, H. (Editor) Marrow, P. (Editor) Shackleton, M. (Editor) |
| Date: | 2002 |
| Status: | Published |
| Publisher: | IEEE, Piscataway, NJ |
| Further Information: | Google Scholar |
| ISI Citation Count: | 4 |
| URI: | http://eprints.soton.ac.uk/id/eprint/259133 |
Actions (login required)
 |
View Item |
