On-chip high-speed sorting of micron-sized particles for high-throughput analysis
Holmes, David, Sandison, Mairi, Green, Nicolas G and Morgan, Hywel (2005) On-chip high-speed sorting of micron-sized particles for high-throughput analysis. IEE Proceedings Nanobiotechnology, 152, (4), 129-134.
A new design of particle sorting chip is presented. The device employs a dielectrophoretic gate that deflects particles into one of two microfluidic channels at high speed. The device operates by focussing particles into the central streamline of the main flow channel using dielectrophoretic focussing. At the sorting junction (T- or Y-junction) two sets of electrodes produce a small dielectrophoretic force that pushes the particle into one or other of the outlet channels, where they are carried under the pressure-driven fluid flow to the outlet. For a 40mm wide and high channel, it is shown that 6micron diameter particles can be deflected at a rate of 300particles/s. The principle of a fully automated sorting device is demonstrated by separating fluorescent from non-fluorescent latex beads.
|Divisions:||Faculty of Physical and Applied Science > Electronics and Computer Science > NANO
|Date Deposited:||08 Mar 2006|
|Last Modified:||02 Mar 2012 11:58|
|Contributors:||Holmes, David (Author)
Sandison, Mairi (Author)
Green, Nicolas G (Author)
Morgan, Hywel (Author)
|Further Information:||Google Scholar|
|ISI Citation Count:||31|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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