Incidence of childhood acute lymphoblastic leukaemia in Yorkshire, UK

Feltbower, Richard G., Moorman, Anthony V., Dovey, Gareth, Kinsey, Sally E. and McKinney, Patricia A. (2001) Incidence of childhood acute lymphoblastic leukaemia in Yorkshire, UK. Lancet, 358, (9279), 385-387. (doi:10.1016/S0140-6736(01)05581-7).


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Between 1980 and 1998, in the north-west of England, a significant rise in childhood acute lymphoblastic leukaemia was caused by an increase in the precursor B-cell form of this disease. We analysed data on children who were diagnosed with leukaemia in Yorkshire, UK, between 1974 and 1997. The incidence of acute lymphoblastic leukaemia remained stable, although a non-significant yearly increase of 2·4% was noted for the precursor B-cell form of this disease from 1980 onwards. The precursor B-cell form accounted for 80% of all acute lymphoblastic leukaemia. Our data are not consistent with increasing incidence for precursor B-cell acute lymphoblastic leukaemia, although numbers of children with acute myeloid leukaemia are rising.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/S0140-6736(01)05581-7
ISSNs: 0140-6736 (print)
Related URLs:
Subjects: H Social Sciences > H Social Sciences (General)
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RJ Pediatrics
Divisions : University Structure - Pre August 2011 > School of Medicine > Cancer Sciences
ePrint ID: 26301
Accepted Date and Publication Date:
Date Deposited: 24 Apr 2006
Last Modified: 31 Mar 2016 11:49

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