Electroporation – how different length and shaped electrical pulses affect the permeability of cells

Daly, K. and Chen, G. (2006) Electroporation – how different length and shaped electrical pulses affect the permeability of cells. At 2006 Annual Report on Conference on Electrical Insulation and Dielectric Phenomena, Kansas City, US, 15 - 18 Oct 2006. IEEE, 353-356.


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Studies into electroporation have grown increasingly popular over the past few years; many studies have been presented both theoretically and practically based. Now presented is a numerical simulation study of the applied pulse amplitude, duration and shape and how these factors relate to the number of pores created during this process. Pulse shapes studied include rectangular, exponential and triangular pulses. Results suggest that out of the most common pulse shapes rectangular pulses are the most efficient pore producers, these results agree with prior studies however disagree with one study, which uses the same model for simulation.

Item Type: Conference or Workshop Item (Speech)
ISBNs: 1424405475 (electronic)
Keywords: electroporation, biological cell, electric pulse, numerical simulation
Subjects: Q Science > QA Mathematics
Q Science > QH Natural history > QH301 Biology
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions : Faculty of Physical Sciences and Engineering > Electronics and Computer Science > EEE
ePrint ID: 263478
Accepted Date and Publication Date:
Date Deposited: 18 Feb 2007
Last Modified: 31 Mar 2016 14:07
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/263478

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