Impedance spectroscopy using maximum length sequences: Application to single cell analysis


Gawad, Shady, Sun, Tao, Green, Nicolas G and Morgan, Hywel (2007) Impedance spectroscopy using maximum length sequences: Application to single cell analysis. Review of Scientific Instruments, 78, 054301. (doi:10.1063/1.2737751).

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Description/Abstract

A maximum length sequence MLS is used to perform broadband impedance spectroscopy on a dielectric sample. The method has a number of advantages over other pulse-based or frequency sweep techniques. It requires the application of a very short sequence of voltage steps in the microsecond range and therefore allows the measurement of time-dependent impedance of a sample with high temporal resolution over a large bandwidth. The technique is demonstrated using a time-invariant passive RC network. The impedance of single biological cell flowing in a microfluidic channel is also measured, showing that MLS is an ideal method for high speed impedance analysis.

Item Type: Article
ISSNs: 0034-6748 (print)
Related URLs:
Divisions: Faculty of Physical Sciences and Engineering > Electronics and Computer Science
ePrint ID: 264101
Date Deposited: 30 May 2007
Last Modified: 03 Dec 2014 12:16
Further Information:Google Scholar
ISI Citation Count:12
URI: http://eprints.soton.ac.uk/id/eprint/264101

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