A gene regulatory network for cell differentiation in Caenorhabditis elegans
Geard, N L and Wiles, J (2003) A gene regulatory network for cell differentiation in Caenorhabditis elegans. In, Abbass, H and Wiles, J (eds.) Proceedings of the First Australian Conference on Artificial Life. The First Australian Conference on Artificial Life , University of New South Wales, 86-100.
Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains enough information to produce a wide variety of specialised cell types, whose spatial and temporal dynamics interact to form intricately detailed patterns and behaviour. Much of the complexity of a developing system lies in the dynamics of gene regulation that occur within each cell. We used a simple recurrent network to model the process of gene regulation and evolved systems that were able to generate the first four cell divisions of the C. elegans cell lineage tree with a high degree of accuracy.
|Item Type:||Book Section|
|Divisions:||Faculty of Physical and Applied Science > Electronics and Computer Science
|Date Deposited:||19 Jun 2007|
|Last Modified:||02 Mar 2012 12:41|
|Contributors:||Geard, N L (Author)
Wiles, J (Author)
Abbass, H (Editor)
Wiles, J (Editor)
|Publisher:||University of New South Wales|
|Further Information:||Google Scholar|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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