Delayed poration after ultrashort electric pulses on Jurkat cell
Delayed poration after ultrashort electric pulses on Jurkat cell
Electrical properties of cancer cells have been studied widely to understand cancer. The increase in electrical conductivity of Jurkat cell suspension after ultrashort electric pulses has been considered as an important phenomenon of the interaction between pulsed electric field and cancer cells. Experimental evidence showed that such an interaction may result in delayed poration. In this paper an attempt has been made to find probability distribution function of poration after ultrashort electric pulses. The conductivity data collected from nanosecond pulse electroporation of Jurkat cancer cells is analysed to form a probability distribution function for pore formation after nanosecond electric field pulse. It has been found that the parameter in the function depends on pulse characteristics such as pulse magnitude, pulse width and number of pulses.
978-961-90234-9-5
1-4
Chen, G.
3de45a9c-6c9a-4bcb-90c3-d7e26be21819
Daly, K.
f40a9985-ef81-4d7e-a7ea-defa8cf8a533
August 2007
Chen, G.
3de45a9c-6c9a-4bcb-90c3-d7e26be21819
Daly, K.
f40a9985-ef81-4d7e-a7ea-defa8cf8a533
Chen, G. and Daly, K.
(2007)
Delayed poration after ultrashort electric pulses on Jurkat cell.
15th International Symposium on High Voltage Engineering, Ljubjana, Slovenia.
27 - 31 Aug 2007.
.
Record type:
Conference or Workshop Item
(Paper)
Abstract
Electrical properties of cancer cells have been studied widely to understand cancer. The increase in electrical conductivity of Jurkat cell suspension after ultrashort electric pulses has been considered as an important phenomenon of the interaction between pulsed electric field and cancer cells. Experimental evidence showed that such an interaction may result in delayed poration. In this paper an attempt has been made to find probability distribution function of poration after ultrashort electric pulses. The conductivity data collected from nanosecond pulse electroporation of Jurkat cancer cells is analysed to form a probability distribution function for pore formation after nanosecond electric field pulse. It has been found that the parameter in the function depends on pulse characteristics such as pulse magnitude, pulse width and number of pulses.
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Published date: August 2007
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CD-ROM
Venue - Dates:
15th International Symposium on High Voltage Engineering, Ljubjana, Slovenia, 2007-08-27 - 2007-08-31
Organisations:
EEE
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Local EPrints ID: 264479
URI: http://eprints.soton.ac.uk/id/eprint/264479
ISBN: 978-961-90234-9-5
PURE UUID: 1fc69a0c-99ff-48b6-bbd7-b9f4bcb51778
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Date deposited: 06 Sep 2007
Last modified: 14 Mar 2024 07:51
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Contributors
Author:
G. Chen
Author:
K. Daly
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