Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system
Sandison, M.E., Zagnoni, M., Abu-Hantash, M. and Morgan, H. (2007) Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system. Journal of Micromechanics and Microengineering, 17, S189-S196.
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Description/Abstract
The use of spark assisted chemical engraving (SACE) to produce glass apertures that are suitable for the formation of artificial bilayer lipid membranes is described. Prior to use, the glass apertures were rendered hydrophobic by a silanization process and were then incorporated into a simple microfluidic device. Successful bilayer lipid membrane (BLM) formation and the subsequent acquisition of single-channel recordings are demonstrated. Due to the simplicity and rapidity of the SACE process, these glass apertures could be easily integrated into an all-glass microfluidic system for BLM formation.
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Physical and Applied Science > Electronics and Computer Science > NANO |
| Item ID: | 264501 |
| Date Deposited: | 14 Sep 2007 |
| Last Modified: | 01 Mar 2012 19:53 |
| Contributors: | Sandison, M.E. (Author) Zagnoni, M. (Author) Abu-Hantash, M. (Author) Morgan, H. (Author) |
| Date: | 2007 |
| Status: | Published |
| Further Information: | Google Scholar |
| ISI Citation Count: | 13 |
| URI: | http://eprints.soton.ac.uk/id/eprint/264501 |
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