Sun, Tao, Bernabini, Catia, Holmes, David, Green, Nicolas G and Morgan, Hywel
High-Throughput, Non-invasive and label-free single cell analysis on a microfluidic chip.
At Electro-active Materials, Cranfield Management Development Centre, Cranfield, UK,
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Cellular analysis requires a combination of biophysical and biochemical approaches for counting, manipulation and characterization of biological cells. In recent years, considerable attentions have been paid to single cell analysis based on lab-on-a-chip (LOC) technology, which offers the characterization of a large amount of cells one by one.Individual cells can be identified and distinguished due to the differences in sizes and dielectric properties using electrical techniques. Electrical impedance spectroscopy (EIS) provides a high speed, non-invasive and label-free technique for single cell analysis.
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