Self-assembly of vesicle nanoarrays on Si: A potential route to high-density functional protein arrays


Ramanujan, C S, Sumitomo, K, de Planque, M R R, Hibino, H, Torimitsu, K and Ryan, J F (2007) Self-assembly of vesicle nanoarrays on Si: A potential route to high-density functional protein arrays. Applied Physics Letters, 90, (3), 033901.

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Description/Abstract

The authors show that 100 nm unilamellar thiol-tagged vesicles bind discretely and specifically to Au nanodots formed on a Si surface. An array of such dots, consisting of 20 nm Au–Si three-dimensional islands, is formed by self-assembly on terraces of small-angle-miscut Si(111)after Au deposition. Consequently, both the formation of the nanopattern and the subsequentattachment of the vesicles are self-organized and occur without the need for any “top-down” lithographic processes. This approach has the potential to provide the basis of a low-cost,high-density nanoarray for use in proteomics and drug discovery.

Item Type: Article
Related URLs:
Divisions: Faculty of Physical Sciences and Engineering > Electronics and Computer Science > NANO
ePrint ID: 264681
Date Deposited: 16 Oct 2007
Last Modified: 27 Mar 2014 20:09
Further Information:Google Scholar
ISI Citation Count:5
URI: http://eprints.soton.ac.uk/id/eprint/264681

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