Holmes, David and Morgan, Hywel
Cell positioning and sorting using dielectrophoresis.
Eur. Cells Mat.
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INTRODUCTION: In this paper we describe a micro-fabricated cell separation and positioning system based on the AC electrokinetic technique, dielectrophoresis (DEP). The system uses nonuniform electric fields produced by arrays of microelectrodes to manipulate cells held in suspension. Depending upon the mode of operation one can either concentrate a single cell type from a heterogeneous mixture (with all other cell types passing through the device); or alternatively separate different cell types along the length of the device. In the second mode of operation the position at which a cell ends up is based on its size and the dielectric properties of its cellular membrane.
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