Development of an EORTC disease-specific quality of life module for use in patients with gastric cancer


Vickery, C.W., Blazeby, J.M., Conroy, T., Arraras, J., Sezer, O., Koller, M., Rosemeyer, D., Johnson, C.D. and Alderson, D. (2001) Development of an EORTC disease-specific quality of life module for use in patients with gastric cancer. European Journal of Cancer, 37, (8), 966-971. (doi:10.1016/S0959-8049(00)00417-2).

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Description/Abstract

Quality of life (QL) is an important outcome in clinical trials in oncology. There is currently no valid international QL measure for gastric cancer. This paper describes the development of a QL module for gastric cancer to supplement the European Organization for Research and Treatment of Cancer (EORTC) Quality of life (QLQ-C30) questionnaire. Phases I to III of module development were conducted in the United Kingdom, France, Germany and Spain according to EORTC QL Group guidelines. Twenty relevant QL issues were generated from the literature and interviews with health professionals (n=24) and patients (n=58). This produced a 24 item provisional module. Further testing in 115 patients resulted in the QLQ-STO22, containing 22 questions, conceptualised into five scales and four single items, related to disease symptoms, treatment side-effects and emotional issues specific to gastric cancer. The use of the QLQ-C30 supplemented by the QLQ-STO22 will provide a comprehensive QL measure for international trials in gastric cancer.

Item Type: Article
ISSNs: 0959-8049 (print)
Related URLs:
Keywords: gastric neoplasm, quality of life, questionnaire, EORTC QLQ-C30, EORTC QLQ-STO22
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: University Structure - Pre August 2011 > School of Medicine > Cancer Sciences
ePrint ID: 26653
Date Deposited: 24 Apr 2006
Last Modified: 27 Mar 2014 18:15
Contact Email Address: jmblazeby@hotmail.com
URI: http://eprints.soton.ac.uk/id/eprint/26653

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