All in the same boat: A “situated” model of emergent immune response

Hebbron, Tom, Noble, Jason and Bullock, Seth (2011) All in the same boat: A “situated” model of emergent immune response. In, George, Kampis, István, Karsai and Eörs, Szathmáry (eds.) Advances in Artificial Life: Tenth European Conference on Artificial Life (ECAL '09). ECAL 2009 , Springer, 353-360.


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Immune systems provide a unique window on the evolution of individuality. Existing models of immune systems fail to consider them as situated within a biochemical context. We present a model that uses an NK landscape as an underlying metabolic substrate, represents organisms as having both internal and external structure, and provides a basis for studying the coevolution of pathogens and host immune responses. Early results from the model are discussed; we show that interaction between organisms drives a population to optima distinct from those found when adapting against an abiotic background.

Item Type: Book Section
Divisions : Faculty of Physical Sciences and Engineering > Electronics and Computer Science > Agents, Interactions & Complexity
ePrint ID: 267670
Accepted Date and Publication Date:
Date Deposited: 17 Jul 2009 00:28
Last Modified: 31 Mar 2016 14:15
Further Information:Google Scholar

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