Multi-objective shape optimization of the human carotid artery
Kolachalama, V.B., Bressloff, N.W. and Nair, P.B. (2005) Multi-objective shape optimization of the human carotid artery. In, Bathe, K.J. (ed.) Computational Fluid and Solid Mechanics 2005: Proceedings, Third MIT Conference on Computational Fluid and Solid Mechanics, June 14-17 2005. Third MIT Conference on Computational Fluid and Solid Mechanics Cambridge, USA, Elsevier, 1310-1314.
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Description/Abstract
A statistical analysis is performed on the key geometric parameters that influence hemodynamics in the human carotid artery bifurcation. A parametric CAD model of the bifurcation is used to automatically construct a range of different geometries. A design of experiments (DoE) approach is employed to generate a set of candidate geometries for flow analysis using an unsteady three dimensional Navier–Stokes solver. The values of the integral of negative average
shear stress (INASS) and the maximal average shear stress (MASS) corresponding to these geometries are then used to construct a Bayesian surrogate model. A shape optimization problem is proposed using the surrogate model which predicts arterial geometries having minimal INASS and MASS.
| Item Type: | Book Section |
|---|---|
| ISBN: | 0080444806 (hardback) 0080444814 (hardback) |
| Related URLs: | http://www.thirdmitconference.org |
| Subjects: | R Medicine > R Medicine (General) T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | University Structure - Pre August 2011 > School of Engineering Sciences |
| ePrint ID: | 26867 |
| Deposited On: | 24 Apr 2006 |
| Last Modified: | 02 Jul 2010 02:59 |
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