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Formation of artificial lipid bilayers using droplet dielectrophoresis

Aghdaei, S, Sandison, ME, Zagnoni, M, Green, NG and Morgan, H (2008) Formation of artificial lipid bilayers using droplet dielectrophoresis. LAB ON A CHIP, 8, 1617-1620.

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Description/Abstract

We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipid-alkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.

Item Type:Article
Additional Information:Imported from ISI Web of Science
Divisions:Faculty of Physical and Applied Science > Electronics and Computer Science > NANO
ePrint ID:269536
Deposited On:21 Apr 2010 08:46
Last Modified:02 Mar 2012 12:22
Further Information:Google Scholar

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