Formation of artificial lipid bilayers using droplet dielectrophoresis


Aghdaei, Sara, Sandison, Mairi E., Zagnoni, Michele, Green, Nichaolas G. and Morgan, Hywel (2008) Formation of artificial lipid bilayers using droplet dielectrophoresis. Lab on a Chip, 8, (10), 1617-1620. (doi:10.1039/B807374K). (PMID:18813381).

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Description/Abstract

We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipid-alkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.

Item Type: Article
ISSNs: 1473-0197 (print)
1473-0189 (electronic)
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Physical and Applied Science > Electronics and Computer Science > NANO
Item ID: 269536
Date Deposited: 21 Apr 2010 07:46
Last Modified: 04 Jul 2012 13:42
Contributors: Aghdaei, Sara (Author)
Sandison, Mairi E. (Author)
Zagnoni, Michele (Author)
Green, Nichaolas G. (Author)
Morgan, Hywel (Author)
Date: 2008
Status: Published
Further Information:Google Scholar
ISI Citation Count:22
URI: http://eprints.soton.ac.uk/id/eprint/269536

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