Basic science and pathophysiology of ocular allergy


Calder, Virginia L. and Lackie, Peter M. (2004) Basic science and pathophysiology of ocular allergy. Current Allergy and Asthma Reports, 4, (4), 326-331.

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Description/Abstract

Ocular allergy includes several clinical subtypes ranging from the mild seasonal allergic conjunctivitis to the potentially sight-threatening atopic keratoconjunctivitis. Current therapies, particularly for the severe forms of disease, need to be more localized and with fewer side effects. For this to be achieved, it requires a better understanding of the basic mechanisms involved. In this chapter, recent findings are discussed that suggest that it is important to take an integrated approach, including both immune and structural elements of the eye. This provides potential new strategies for therapy, addressing the influence of structural cells in disease. These might influence the immune processes that take place and, as the structural cells are precisely localized, topical application is likely to be effective.

Item Type: Article
ISSNs: 1529-7322 (print)
Related URLs:
Subjects: R Medicine > RE Ophthalmology
Q Science > QR Microbiology > QR180 Immunology
Q Science > QP Physiology
Divisions: University Structure - Pre August 2011 > School of Medicine > Infection, Inflammation and Repair
ePrint ID: 26977
Date Deposited: 26 Apr 2006
Last Modified: 27 Mar 2014 18:15
Contact Email Address: p.m.lackie@soton.ac.uk
URI: http://eprints.soton.ac.uk/id/eprint/26977

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