Resolution of peanut allergy following bone marrow transplantation for primary immunodeficiency
Resolution of peanut allergy following bone marrow transplantation for primary immunodeficiency
Peanut allergy is a severe and life-threatening form of food allergy. Treatments are being developed but the mainstays of current management remain avoidance of peanut and appropriate use of rescue medication. We report the case of a boy with peanut allergy who required a bone marrow transplant (BMT) for combined immunodeficiency. A food challenge, 2 years after transplant, showed that his peanut allergy had resolved. Allergic disorders constitute a form of immune deviation and while we do not advocate BMT as a treatment for peanut allergy, we believe this case provides an insight into the basic mechanisms involved in food allergy.
536-537
Hourihane, J.O.
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Rhodes, H.L.
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Jones, A.M.
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Veys, P.
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Connett, G.J.
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2005
Hourihane, J.O.
01ba1495-72e1-4522-b627-60a7d31aae20
Rhodes, H.L.
b1b7bc9c-9807-4f65-bd4d-9cb9cc12477a
Jones, A.M.
9f3a310d-f9d8-467f-bbc0-d210659ca7c4
Veys, P.
9ccba2d2-39a1-402a-a6e9-61b9476fe1e5
Connett, G.J.
55d5676c-90d8-46bf-a508-62eded276516
Hourihane, J.O., Rhodes, H.L., Jones, A.M., Veys, P. and Connett, G.J.
(2005)
Resolution of peanut allergy following bone marrow transplantation for primary immunodeficiency.
Allergy, 60 (4), .
(doi:10.1111/j.1398-9995.2005.00752.x).
Abstract
Peanut allergy is a severe and life-threatening form of food allergy. Treatments are being developed but the mainstays of current management remain avoidance of peanut and appropriate use of rescue medication. We report the case of a boy with peanut allergy who required a bone marrow transplant (BMT) for combined immunodeficiency. A food challenge, 2 years after transplant, showed that his peanut allergy had resolved. Allergic disorders constitute a form of immune deviation and while we do not advocate BMT as a treatment for peanut allergy, we believe this case provides an insight into the basic mechanisms involved in food allergy.
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Published date: 2005
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Local EPrints ID: 27150
URI: http://eprints.soton.ac.uk/id/eprint/27150
ISSN: 0105-4538
PURE UUID: 332d5b93-414f-497c-9fda-5ae62179c36a
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Date deposited: 25 Apr 2006
Last modified: 16 Mar 2024 04:35
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Author:
J.O. Hourihane
Author:
H.L. Rhodes
Author:
A.M. Jones
Author:
P. Veys
Author:
G.J. Connett
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