Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments


Treweek, Shaun, Ricketts, Ian W., Francis, Jullian, Eccles, Martin, Bonetti, Debbie, Pitts, Nigel B., MacLennan, Graeme, Sullivan, Frank, Jones, Claire, Weal, Mark and Barnett, Karen (2011) Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments. Implementation Science, 6, (16)

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Description/Abstract

Background Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision. Methods The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate. Discussion More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the National Health Service where behaviour needs to be modified, including interventions aimed directly at the public. Trial registration Current Controlled Trials NCT01206738.

Item Type: Article
Related URLs:
Divisions: Faculty of Physical and Applied Science > Electronics and Computer Science > Web & Internet Science
Item ID: 272080
Date Deposited: 03 Mar 2011 17:22
Last Modified: 25 Aug 2012 02:27
Contributors: Treweek, Shaun (Author)
Ricketts, Ian W. (Author)
Francis, Jullian (Author)
Eccles, Martin (Author)
Bonetti, Debbie (Author)
Pitts, Nigel B. (Author)
MacLennan, Graeme (Author)
Sullivan, Frank (Author)
Jones, Claire (Author)
Weal, Mark (Author)
Barnett, Karen (Author)
Date: 3 March 2011
Status: Published
Publisher: BioMed Central
Further Information:Google Scholar
ISI Citation Count:1
URI: http://eprints.soton.ac.uk/id/eprint/272080

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