Patterns in randomly evolving networks: Idiotypic networks


Brede, Markus and Behn, Ulrich (2003) Patterns in randomly evolving networks: Idiotypic networks. Physical Review E, 67, (3) (doi:10.1103/PhysRevE.67.031920).

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Description/Abstract

We present a model for the evolution of networks of occupied sites on undirected regular graphs. At every iteration step in a parallel update, I randomly chosen empty sites are occupied and occupied sites having occupied neighbor degree outside of a given interval (t(l),t(u)) are set empty. Depending on the influx I and the values of both lower threshold and upper threshold of the occupied neighbor degree, different kinds of behavior can be observed. In certain regimes stable long-living patterns appear. We distinguish two types of patterns: static patterns arising on graphs with low connectivity and dynamic patterns found on high connectivity graphs. Increasing I patterns become unstable and transitions between almost stable patterns, interrupted by disordered phases, occur. For still larger I the lifetime of occupied sites becomes very small and network structures are dominated by randomness. We develop methods to analyze the nature and dynamics of these network patterns, give a statistical description of defects and fluctuations around them, and elucidate the transitions between different patterns. Results and methods presented can be applied to a variety of problems in different fields and a broad class of graphs. Aiming chiefly at the modeling of functional networks of interacting antibodies and B cells of the immune system (idiotypic networks), we focus on a class of graphs constructed by bit chains. The biological relevance of the patterns and possible operational modes of idiotypic networks are discussed.

Item Type: Article
ISSNs: 1539-3755
Divisions: Faculty of Physical and Applied Science > Electronics and Computer Science > Agents, Interactions & Complexity
Item ID: 272891
Date Deposited: 29 Sep 2011 16:31
Last Modified: 02 Mar 2012 11:41
Contributors: Brede, Markus (Author)
Behn, Ulrich (Author)
Date: 2003
Status: Published
Publisher: The American Physical Society
Further Information:Google Scholar
ISI Citation Count:10
URI: http://eprints.soton.ac.uk/id/eprint/272891

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