Matrix metalloproteinases and the gut - new roles for old enzymes

Pender, Sylvia L. F. and MacDonald, Thomas T (2004) Matrix metalloproteinases and the gut - new roles for old enzymes. Current Opinion in Pharmacology, 4, (6), 546-550. (doi:10.1016/j.coph.2004.06.005).


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Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and cancer. Recent data suggest that MMPs are involved in tissue injury and healing in the human gut.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/j.coph.2004.06.005
ISSNs: 1471-4892 (print)
Related URLs:
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions : University Structure - Pre August 2011 > School of Medicine > Infection, Inflammation and Repair
ePrint ID: 27322
Accepted Date and Publication Date:
Date Deposited: 25 Apr 2006
Last Modified: 31 Mar 2016 11:51

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