Epidemiology of central nervous system tumors in children and young adults (0-29 years), Yorkshire, United Kingdom


Feltbower, R., Picton, S., Bridges, L., Crooks, D., Glaser, A. and McKinney, P. (2004) Epidemiology of central nervous system tumors in children and young adults (0-29 years), Yorkshire, United Kingdom. Pediatric Hematology and Oncology, 21, (7), 647-660. (doi:10.1080/08880010490501079).

Download

Full text not available from this repository.

Description/Abstract

The authors describe the incidence and survival of 480 patients diagnosed under 30 years with a CNS tumor in Yorkshire, UK between 1990 and 2001. The effect on survival from deprivation and other prognostic factors was examined. Young adults (aged 15–29) were significantly less likely to develop CNS tumors than children (p = .001), largely because of an excess of medulloblastoma and ependymoma in the pediatric age range. No significant temporal trends in incidence were present apart from young adults with “other CNS” tumors showing an average annual increase of 10.7% (95% CI 1.3–21.0%; p = .03). Young adults had significantly lower survival rates than children (hazard ratio = 1.52, 95%CI 1.10–2.10). The highest risk of death was observed for patients from the most affluent areas. The overall burden of CNS tumors appears to be relatively constant, but the significantly poorer survival for young people needs further rapid investigation.

Item Type: Article
ISSNs: 0888-0018 (print)
Related URLs:
Keywords: adolescent, brain, central nervous system tumor, child, epidemiology
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RJ Pediatrics
Divisions: University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences
ePrint ID: 27571
Date Deposited: 27 Apr 2006
Last Modified: 27 Mar 2014 18:16
URI: http://eprints.soton.ac.uk/id/eprint/27571

Actions (login required)

View Item View Item