Assessing subjective sleep reports in the first-degree relatives of antidepressant-treated depressed outpatients

Mayers, Andrew G., van Hooff, Johanna C. and Baldwin, David S. (2003) Assessing subjective sleep reports in the first-degree relatives of antidepressant-treated depressed outpatients. Human Psychopharmacology: Clinical and Experimental, 18, (3), 207-214. (doi:10.1002/hup.475).


Full text not available from this repository.

Original Publication URL:


This study sought to investigate whether first-degree relatives of depressed patients report, and react to, sleep perceptions in the same way as the depressed group. Our previous research suggested that depressed individuals may experience greater sleep distress than healthy individuals; we wished to explore whether this was also apparent in their nearest relatives. A sample was recruited of 18 antidepressant-treated patients with a current DSM-IV diagnosis of major depressive disorder, 18 healthy controls, and a group of 10 first-degree relatives for each study group. In accordance with previous findings, poorer sleep perceptions corresponded with poorer life-quality and mood perceptions, and depressed individuals reported poorer sleep perceptions and poorer life-quality/mood perceptions than controls. Additionally, there was evidence of similar sleep reporting between depressed patients and their relatives, and for a difference between these relatives and other non-depressed groups. There was a non-significant trend for depressed patients, and their relatives, to report total sleep time in the same manner as each other, and differently to other non-depressed groups. Reports of poor sleep may be associated with reports of poor mood in depression, but in non-depressed individuals the association may be with a feeling of weariness.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1002/hup.475
Related URLs:
Keywords: subjective sleep quality, depression, first-degree relatives
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
B Philosophy. Psychology. Religion > BF Psychology
Divisions : University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences
ePrint ID: 27647
Accepted Date and Publication Date:
Date Deposited: 28 Apr 2006
Last Modified: 31 Mar 2016 11:52

Actions (login required)

View Item View Item