A new role for astrocytes: β-amyloid homeostasis and degradation
Nicoll, James A.R. and Weller, Roy O. (2003) A new role for astrocytes: β-amyloid homeostasis and degradation. Trends in Molecular Medicine, 9, (7), 281-282. (doi:10.1016/S1471-4914(03)00109-6).
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Original Publication URL: http://dx.doi.org/10.1016/S1471-4914(03)00109-6
Description/Abstract
Accumulation of β-amyloid protein (Aβ) in the brain is believed to play a key role in the pathogenesis of Alzheimer's disease (AD). There is evidence that Aβ accumulation might result from decreased elimination from the brain as well as from increased production, and recent work has suggested that astrocytes could have a role in Aβ degradation. This might lead to a better understanding of AD pathogenesis and possibly to new therapeutic avenues.
| Item Type: | Article |
|---|---|
| ISSNs: | 1471-4914 (print) |
| Related URLs: | |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences |
| Item ID: | 27674 |
| Date Deposited: | 28 Apr 2006 |
| Last Modified: | 02 Mar 2012 12:46 |
| Contributors: | Nicoll, James A.R. (Author) Weller, Roy O. (Author) |
| Date: | 2003 |
| Status: | Published |
| Contact Email Address: | j.nicoll@soton.ac.uk |
| URI: | http://eprints.soton.ac.uk/id/eprint/27674 |
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