Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation
Thornton, A.R.D., Shin, K., Gottesman, E. and Hine, J. (2001) Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation. Clinical Neurophysiology, 112, (5), 768-777. (doi:10.1016/S1388-2457(01)00484-9).
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Description/Abstract
Objectives: the objective of this study was to examine whether temporal non-linearities of the cochlear amplifier, as reflected by otoacoustic emissions (OAEs), exist and are distinct from any recording system non-linearities.
Methods: maximum length sequence stimulation, at various stimulus rates, was used to evoke OAEs from normally hearing subjects. Recordings from a 2cc cavity were also made. The data were analyzed to obtain the linear response and estimates of the slices of the 2nd and 3rd order Volterra kernels. This provided a measure of two and 3 click non-linear temporal interactions, respectively.
Results: the results showed that temporal non-linearities of OAEs do exist, are stable and repeatable within individuals and have properties that differ from those shown by the conventional linear response. Whilst some of the non-linear response properties conformed to the expected pattern, of increasing amplitude with increase in stimulus rate, there are some areas in which they show an unpredicted complexity.
Conclusions: whilst system non-linearities could be found, there was no difficulty in distinguishing between the physiological and system non-linear components. New areas of research and application may result from the use of these new OAE responses.
| Item Type: | Article |
|---|---|
| ISSNs: | 1388-2457 (print) |
| Related URLs: | |
| Keywords: | non-linear systems, maximum length sequences, cochlear amplifier, otoacoustic emissions, volterra kernels, volterra series |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RF Otorhinolaryngology Q Science > QP Physiology |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences |
| Item ID: | 27727 |
| Date Deposited: | 27 Apr 2006 |
| Last Modified: | 01 Jun 2011 11:25 |
| Contributors: | Thornton, A.R.D. (Author) Shin, K. (Author) Gottesman, E. (Author) Hine, J. (Author) |
| Date: | May 2001 |
| Status: | Published |
| Contact Email Address: | ardt@soton.ac.uk |
| URI: | http://eprints.soton.ac.uk/id/eprint/27727 |
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