Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation
Thornton, A.R.D., Shin, K., Gottesman, E. and Hine, J. (2001) Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation. Clinical Neurophysiology, 112, (5), 768-777. (doi:10.1016/S1388-2457(01)00484-9).
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Objectives: the objective of this study was to examine whether temporal non-linearities of the cochlear amplifier, as reflected by otoacoustic emissions (OAEs), exist and are distinct from any recording system non-linearities.
Methods: maximum length sequence stimulation, at various stimulus rates, was used to evoke OAEs from normally hearing subjects. Recordings from a 2cc cavity were also made. The data were analyzed to obtain the linear response and estimates of the slices of the 2nd and 3rd order Volterra kernels. This provided a measure of two and 3 click non-linear temporal interactions, respectively.
Results: the results showed that temporal non-linearities of OAEs do exist, are stable and repeatable within individuals and have properties that differ from those shown by the conventional linear response. Whilst some of the non-linear response properties conformed to the expected pattern, of increasing amplitude with increase in stimulus rate, there are some areas in which they show an unpredicted complexity.
Conclusions: whilst system non-linearities could be found, there was no difficulty in distinguishing between the physiological and system non-linear components. New areas of research and application may result from the use of these new OAE responses.
|Keywords:||non-linear systems, maximum length sequences, cochlear amplifier, otoacoustic emissions, volterra kernels, volterra series|
|Subjects:||R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RF Otorhinolaryngology
Q Science > QP Physiology
|Divisions:||University Structure - Pre August 2011 > School of Medicine > Clinical Neurosciences
|Date Deposited:||27 Apr 2006|
|Last Modified:||27 Mar 2014 18:16|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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