The University of Southampton
University of Southampton Institutional Repository

The auditory middle latency response, evoked using maximum length sequences and chirps, as an indicator of adequacy of anesthesia

The auditory middle latency response, evoked using maximum length sequences and chirps, as an indicator of adequacy of anesthesia
The auditory middle latency response, evoked using maximum length sequences and chirps, as an indicator of adequacy of anesthesia
The auditory evoked potential known as the middle latency response (MLR), evoked with regular click stimulation at around 5 Hz, has been suggested as an indicator of adequacy of anesthesia. The MLR is a very small signal embedded in high levels of background noise, so it can take a long time to acquire. However, using a stimulus paradigm of chirps presented in a maximum length sequence, the acquisition of the MLR can be improved compared to using conventional click stimulation. In this pilot study, we investigated this new technique in a clinical environment. Significant changes in MLR amplitude, but not latency, were measured for six of seven subjects in association with changes in responsiveness to command using the isolated forearm technique. The absence of any latency shift differs from other studies of the MLR during anesthesia and highlights the limited understanding of the relationship between anesthesia and the MLR.
0003-2999
495-498
Bell, Steven L.
91de0801-d2b7-44ba-8e8e-523e672aed8a
Smith, David C.
cc2ef49e-7c4a-4476-9ed0-18ec22976bf1
Allen, Robert
956a918f-278c-48ef-8e19-65aa463f199a
Lutman, Mark E.
Bell, Steven L.
91de0801-d2b7-44ba-8e8e-523e672aed8a
Smith, David C.
cc2ef49e-7c4a-4476-9ed0-18ec22976bf1
Allen, Robert
956a918f-278c-48ef-8e19-65aa463f199a
Lutman, Mark E.

Bell, Steven L., Smith, David C., Allen, Robert and Lutman, Mark E. (2006) The auditory middle latency response, evoked using maximum length sequences and chirps, as an indicator of adequacy of anesthesia. Anesthesia and Analgesia, 102 (2), 495-498. (doi:10.1213/01.ane.0000189191.71449.48).

Record type: Article

Abstract

The auditory evoked potential known as the middle latency response (MLR), evoked with regular click stimulation at around 5 Hz, has been suggested as an indicator of adequacy of anesthesia. The MLR is a very small signal embedded in high levels of background noise, so it can take a long time to acquire. However, using a stimulus paradigm of chirps presented in a maximum length sequence, the acquisition of the MLR can be improved compared to using conventional click stimulation. In this pilot study, we investigated this new technique in a clinical environment. Significant changes in MLR amplitude, but not latency, were measured for six of seven subjects in association with changes in responsiveness to command using the isolated forearm technique. The absence of any latency shift differs from other studies of the MLR during anesthesia and highlights the limited understanding of the relationship between anesthesia and the MLR.

This record has no associated files available for download.

More information

Published date: February 2006
Organisations: Human Sciences Group

Identifiers

Local EPrints ID: 28409
URI: http://eprints.soton.ac.uk/id/eprint/28409
ISSN: 0003-2999
PURE UUID: 19b3ab18-fb3d-4e36-988c-7c71f8957ee7

Catalogue record

Date deposited: 28 Apr 2006
Last modified: 15 Mar 2024 07:24

Export record

Altmetrics

Contributors

Author: Steven L. Bell
Author: David C. Smith
Author: Robert Allen
Author: Mark E. Lutman

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×