Mathematical models for the early detection and treatment of colorectal cancer

Harper, P. and Jones, S. (2005) Mathematical models for the early detection and treatment of colorectal cancer. Health Care Management Science, 8, (2), 101-109. (doi:10.1007/s10729-005-0393-7).


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Colorectal cancer is a major cause of death for men and women in the Western world. When the cancer is detected through an awareness of the symptoms by a patient, typically it is at an advanced stage. It is possible to detect cancer at an early stage through screening and the marked differences in survival for early and late stages provide the incentive for the primary prevention or early detection of colorectal cancer. This paper considers mathematical models for colorectal cancer screening together with models for the treatment of patients. Illustrative results demonstrate that detailed attention to the processes involved in diseases, interventions and treatment enable us to combine data and expert knowledge from various sources. Thus a detailed operational model is a very useful tool in helping to make decisions about screening at national and local levels.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1007/s10729-005-0393-7
ISSNs: 1386-9620 (print)
Related URLs:
Keywords: colorectal cancer, screening, health care modelling, simulation
Subjects: Q Science > QA Mathematics
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions : University Structure - Pre August 2011 > School of Mathematics > Operational Research
ePrint ID: 29709
Accepted Date and Publication Date:
Date Deposited: 11 May 2006
Last Modified: 31 Mar 2016 11:55

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