Efficient directional inference methodologies for the comparisons of three ordered treatment effects


Hayter, Anthony, Miwa, Tetsushisa and Liu, Wei (2001) Efficient directional inference methodologies for the comparisons of three ordered treatment effects. Journal of the Japan Statistical Society, 31, (2), 153-174.

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Description/Abstract

We consider the unbalanced one-way layout for comparing 3 treatment effects which can be assumed to satisfy the simple ordering m1 m2 m3. This problem arises often in the comparison of three dose levels in medical trials, for example. The one-sided studentised range test provides a set of simultaneous confidence intervals for the ordered pairwise differences mj - mi, i < j which are one-sided and have infinite upper bounds. The new confidence interval procedure proposed in this article maintains the sensitivity of the one-sided studentised range test in detecting each of the ordered differences mj - mi > 0 while at the same time providing two-sided finite confidence intervals. Consequently, this new procedure has the advantage of allowing the same directional inferences as the one-sided studentised range test while additionally providing upper bounds on the differences among the treatment effects.

Item Type: Article
Related URLs:
Keywords: analysis of variance, bioassay, directional errors, medical trials, multiple comparisons, simultaneous inference, order restricted inference, experimentwise error rate
Subjects: Q Science > QA Mathematics
H Social Sciences > HA Statistics
Divisions: University Structure - Pre August 2011 > School of Mathematics > Statistics
ePrint ID: 30108
Date Deposited: 12 May 2006
Last Modified: 27 Mar 2014 18:18
URI: http://eprints.soton.ac.uk/id/eprint/30108

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