Aldol elaboration of 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridin-4-ones, masked precursors to acylpyridones


Jones, Raymond C F, Choudhury, Abdul K, Iley, James N, Light, Mark E, Loizou, Georgia and Pillainayagam, Terence A (2012) Aldol elaboration of 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridin-4-ones, masked precursors to acylpyridones. Beilstein Journal of Organic Chemistry, 8, 308-312. (doi:10.3762/bjoc.8.33).

Download

Full text not available from this repository.

Description/Abstract

A core 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-one scaffold is elaborated at C-3(Me) by base-mediated aldol condensation to give new 3-alkenyl-4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-ones, which are masked forms related to the acylpyridone natural products

Item Type: Article
ISSNs: 1860-5397 (print)
1860-5397 (electronic)
Keywords: aldol reaction, fused-ring systems, heterocycles, isoxazole, metalation, pyridone
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural and Environmental Sciences > Chemistry
ePrint ID: 336655
Date Deposited: 02 Apr 2012 15:07
Last Modified: 27 Mar 2014 20:20
URI: http://eprints.soton.ac.uk/id/eprint/336655

Actions (login required)

View Item View Item