The first total synthesis of (+)-mucosin


Henderson, Alan R., Stec, Jozef, Owen, David R. and Whitby, Richard J. (2012) The first total synthesis of (+)-mucosin. Chemical Communications, 48, (28), 3409-3411. (doi:10.1039/c2cc17915f). (PMID:22358150).

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Description/Abstract

The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous stereocentres around the unusual bicyclo[4.3.0]nonene core.

Item Type: Article
ISSNs: 1359-7345 (print)
1364-548X (electronic)
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Natural and Environmental Sciences
Faculty of Natural and Environmental Sciences > Chemistry
Faculty of Natural and Environmental Sciences > Chemistry > Molecular Assembly, Function & Structure
Faculty of Natural and Environmental Sciences > Chemistry > Synthetic Chemistry Group
ePrint ID: 337314
Date Deposited: 24 Apr 2012 09:22
Last Modified: 27 Mar 2014 20:20
URI: http://eprints.soton.ac.uk/id/eprint/337314

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