The first total synthesis of (+)-mucosin


Henderson, Alan R., Stec, Jozef, Owen, David R. and Whitby, Richard J. (2012) The first total synthesis of (+)-mucosin. Chemical Communications, 48, (28), 3409-3411. (doi:10.1039/c2cc17915f). (PMID:22358150).

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Description/Abstract

The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous stereocentres around the unusual bicyclo[4.3.0]nonene core.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1039/c2cc17915f
ISSNs: 1359-7345 (print)
1364-548X (electronic)
Subjects: Q Science > QD Chemistry
Divisions : Faculty of Natural and Environmental Sciences
Faculty of Natural and Environmental Sciences > Chemistry
Faculty of Natural and Environmental Sciences > Chemistry > Organic Chemistry: Synthesis, Catalysis and Flow
Faculty of Natural and Environmental Sciences > Chemistry > Characterisation and Analytics
ePrint ID: 337314
Accepted Date and Publication Date:
Status
10 February 2012Published
Date Deposited: 24 Apr 2012 09:22
Last Modified: 31 Mar 2016 14:26
URI: http://eprints.soton.ac.uk/id/eprint/337314

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