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Donepezil and memantine for moderate-to-severe Alzheimer's disease

Donepezil and memantine for moderate-to-severe Alzheimer's disease
Donepezil and memantine for moderate-to-severe Alzheimer's disease
In patients with moderate or severe Alzheimer's disease, continued treatment with donepezil was associated with cognitive benefits that exceeded the minimum clinically important difference and with significant functional benefits over the course of 12 months.
893-903
Howard, Robert
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McShane, Rupert
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Lindesay, James
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Ritchie, Craig
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Baldwin, Ashley
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Barber, Robert
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Burns, Alistair
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Dening, Tom
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Findlay, David
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Holmes, Clive
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Jones, Rob
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Jones, Roy
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McKeith, Ian
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Macharouthu, Ajay
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O'Brien, John
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Passmore, Peter
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Sheehan, Bart
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Juszczak, Edmund
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Katona, Cornelius
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Hills, Robert
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Knapp, Martin
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Ballard, Clive
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Brown, Richard
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Banerjee, Sube
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Onions, Caroline
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Adams, Jessica
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Gray, Richard
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Johnson, Tony
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Bentham, Peter
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Phillips, Patrick
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Howard, Robert
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Lindesay, James
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Baldwin, Ashley
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Barber, Robert
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Burns, Alistair
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Dening, Tom
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Findlay, David
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Holmes, Clive
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Jones, Roy
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McKeith, Ian
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Macharouthu, Ajay
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O'Brien, John
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Passmore, Peter
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Sheehan, Bart
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Juszczak, Edmund
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Katona, Cornelius
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Hills, Robert
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Knapp, Martin
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Ballard, Clive
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Brown, Richard
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Banerjee, Sube
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Onions, Caroline
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Griffin, Mary
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Adams, Jessica
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Gray, Richard
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Johnson, Tony
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Bentham, Peter
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Phillips, Patrick
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Howard, Robert, McShane, Rupert, Lindesay, James, Ritchie, Craig, Baldwin, Ashley, Barber, Robert, Burns, Alistair, Dening, Tom, Findlay, David, Holmes, Clive, Hughes, Alan, Jacoby, Robin, Jones, Rob, Jones, Roy, McKeith, Ian, Macharouthu, Ajay, O'Brien, John, Passmore, Peter, Sheehan, Bart, Juszczak, Edmund, Katona, Cornelius, Hills, Robert, Knapp, Martin, Ballard, Clive, Brown, Richard, Banerjee, Sube, Onions, Caroline, Griffin, Mary, Adams, Jessica, Gray, Richard, Johnson, Tony, Bentham, Peter and Phillips, Patrick (2012) Donepezil and memantine for moderate-to-severe Alzheimer's disease. New England Journal of Medicine, 366 (10), 893-903. (doi:10.1056/NEJMoa1106668). (PMID:22397651)

Record type: Article

Abstract

In patients with moderate or severe Alzheimer's disease, continued treatment with donepezil was associated with cognitive benefits that exceeded the minimum clinically important difference and with significant functional benefits over the course of 12 months.

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More information

Published date: 8 March 2012
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 337604
URI: http://eprints.soton.ac.uk/id/eprint/337604
DOI: doi:10.1056/NEJMoa1106668
PURE UUID: bfa0a3fa-fe57-4f2d-aeea-412fb872771c
ORCID for Clive Holmes: ORCID iD orcid.org/0000-0003-1999-6912

Catalogue record

Date deposited: 01 May 2012 09:16
Last modified: 15 Mar 2024 03:01

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Contributors

Author: Robert Howard
Author: Rupert McShane
Author: James Lindesay
Author: Craig Ritchie
Author: Ashley Baldwin
Author: Robert Barber
Author: Alistair Burns
Author: Tom Dening
Author: David Findlay
Author: Clive Holmes ORCID iD
Author: Alan Hughes
Author: Robin Jacoby
Author: Rob Jones
Author: Roy Jones
Author: Ian McKeith
Author: Ajay Macharouthu
Author: John O'Brien
Author: Peter Passmore
Author: Bart Sheehan
Author: Edmund Juszczak
Author: Cornelius Katona
Author: Robert Hills
Author: Martin Knapp
Author: Clive Ballard
Author: Richard Brown
Author: Sube Banerjee
Author: Caroline Onions
Author: Mary Griffin
Author: Jessica Adams
Author: Richard Gray
Author: Tony Johnson
Author: Peter Bentham
Author: Patrick Phillips

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