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Ureaplasma: pathogen or passenger in neonatal meningitis?

Ureaplasma: pathogen or passenger in neonatal meningitis?
Ureaplasma: pathogen or passenger in neonatal meningitis?
The significance of Ureaplasma species as pathogens in neonatal meningitis remains contentious. Using an illustrative case of a premature infant with Ureaplasma parvum meningitis, confirmed by cerebrospinal fluid cultures and both specific and 16s rDNA polymerase chain reaction, we discuss the epidemiology of Ureaplasma species, the difficulties involved in diagnosis and establishing pathogenicity, and the challenges in defining appropriate treatment.
60-64
Clifford, V.
aea0526f-799b-47ec-b92f-541cb0dee489
Tebruegge, M.
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Everest, N.
bd86c06c-b372-47c9-90e2-f2270325d1f4
Curtis, N.
f12bb8b9-1dd8-42c3-b0a8-93cb0005d5cb
Clifford, V.
aea0526f-799b-47ec-b92f-541cb0dee489
Tebruegge, M.
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Everest, N.
bd86c06c-b372-47c9-90e2-f2270325d1f4
Curtis, N.
f12bb8b9-1dd8-42c3-b0a8-93cb0005d5cb

Clifford, V., Tebruegge, M., Everest, N. and Curtis, N. (2010) Ureaplasma: pathogen or passenger in neonatal meningitis? Pediatric Infectious Disease Journal, 29 (1), 60-64. (doi:10.1097/INF.0b013e3181b21016). (PMID:19910840)

Record type: Article

Abstract

The significance of Ureaplasma species as pathogens in neonatal meningitis remains contentious. Using an illustrative case of a premature infant with Ureaplasma parvum meningitis, confirmed by cerebrospinal fluid cultures and both specific and 16s rDNA polymerase chain reaction, we discuss the epidemiology of Ureaplasma species, the difficulties involved in diagnosis and establishing pathogenicity, and the challenges in defining appropriate treatment.

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Published date: January 2010
Organisations: Faculty of Medicine

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Local EPrints ID: 337635
URI: http://eprints.soton.ac.uk/id/eprint/337635
DOI: doi:10.1097/INF.0b013e3181b21016
PURE UUID: a4f29037-2b25-4d5a-bcf3-72944376b8c3

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Date deposited: 01 May 2012 15:54
Last modified: 14 Mar 2024 10:56

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Contributors

Author: V. Clifford
Author: M. Tebruegge
Author: N. Everest
Author: N. Curtis

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