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Nitrate and nitrite in biology, nutrition and therapeutics

Nitrate and nitrite in biology, nutrition and therapeutics
Nitrate and nitrite in biology, nutrition and therapeutics
Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is emerging as an important mediator of blood flow regulation, cell signaling, energetics and tissue responses to hypoxia. The latest advances in our understanding of the biochemistry, physiology and therapeutics of nitrate, nitrite and NO were discussed during a recent 2-day meeting at the Nobel Forum, Karolinska Institutet in Stockholm.
1552-4450
865-869
Lundberg, Jon O.
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Gladwin, Mark T.
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Ahluwalia, Amrita
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Benjamin, Nigel
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Bryan, Nathan S.
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Butler, Anthony
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Cabrales, Pedro
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Fago, Angela
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Feelisch, Martin
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Ford, Peter C.
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Freeman, Bruce A.
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Frenneaux, Michael
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Friedman, Joel
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Kelm, Malte
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Kevil, Christopher G.
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Kim-Shapiro, Daniel B.
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Kozlov, Andrey V.
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Lancaster Jr, Jack R.
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Lefer, David J.
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McColl, Kenneth
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McCurry, Kenneth
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Patel, Rakesh P.
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Petersson, Joel
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Rassaf, Tienush
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Reutov, Valentin P.
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Richter-Addo, George B.
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Schechter, Alan
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Shiva, Sruti
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Tsuchiya, Koichiro
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van Faassen, Ernst E.
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Webb, Andrew J.
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Zuckerbraun, Brian S.
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Zweier, Jay L.
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Weitzberg, Eddie
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Lundberg, Jon O.
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Gladwin, Mark T.
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Ahluwalia, Amrita
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Benjamin, Nigel
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Bryan, Nathan S.
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Butler, Anthony
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Cabrales, Pedro
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Fago, Angela
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Feelisch, Martin
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Ford, Peter C.
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Freeman, Bruce A.
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Frenneaux, Michael
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Friedman, Joel
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Kelm, Malte
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Kevil, Christopher G.
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Kim-Shapiro, Daniel B.
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Kozlov, Andrey V.
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Lancaster Jr, Jack R.
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Lefer, David J.
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McColl, Kenneth
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McCurry, Kenneth
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Patel, Rakesh P.
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Petersson, Joel
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Rassaf, Tienush
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Reutov, Valentin P.
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Richter-Addo, George B.
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Schechter, Alan
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Shiva, Sruti
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Tsuchiya, Koichiro
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van Faassen, Ernst E.
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Webb, Andrew J.
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Zuckerbraun, Brian S.
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Zweier, Jay L.
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Weitzberg, Eddie
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Lundberg, Jon O., Gladwin, Mark T., Ahluwalia, Amrita, Benjamin, Nigel, Bryan, Nathan S., Butler, Anthony, Cabrales, Pedro, Fago, Angela, Feelisch, Martin, Ford, Peter C., Freeman, Bruce A., Frenneaux, Michael, Friedman, Joel, Kelm, Malte, Kevil, Christopher G., Kim-Shapiro, Daniel B., Kozlov, Andrey V., Lancaster Jr, Jack R., Lefer, David J., McColl, Kenneth, McCurry, Kenneth, Patel, Rakesh P., Petersson, Joel, Rassaf, Tienush, Reutov, Valentin P., Richter-Addo, George B., Schechter, Alan, Shiva, Sruti, Tsuchiya, Koichiro, van Faassen, Ernst E., Webb, Andrew J., Zuckerbraun, Brian S., Zweier, Jay L. and Weitzberg, Eddie (2009) Nitrate and nitrite in biology, nutrition and therapeutics. Nature Chemical Biology, 5 (12), 865-869. (doi:10.1038/nchembio.260). (PMID:19915529)

Record type: Article

Abstract

Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is emerging as an important mediator of blood flow regulation, cell signaling, energetics and tissue responses to hypoxia. The latest advances in our understanding of the biochemistry, physiology and therapeutics of nitrate, nitrite and NO were discussed during a recent 2-day meeting at the Nobel Forum, Karolinska Institutet in Stockholm.

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More information

Published date: December 2009
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 337700
URI: http://eprints.soton.ac.uk/id/eprint/337700
DOI: doi:10.1038/nchembio.260
ISSN: 1552-4450
PURE UUID: 9bd46797-1d40-40db-874a-9a2f1283739b
ORCID for Martin Feelisch: ORCID iD orcid.org/0000-0003-2320-1158

Catalogue record

Date deposited: 02 May 2012 13:01
Last modified: 15 Mar 2024 03:41

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Contributors

Author: Jon O. Lundberg
Author: Mark T. Gladwin
Author: Amrita Ahluwalia
Author: Nigel Benjamin
Author: Nathan S. Bryan
Author: Anthony Butler
Author: Pedro Cabrales
Author: Angela Fago
Author: Martin Feelisch ORCID iD
Author: Peter C. Ford
Author: Bruce A. Freeman
Author: Michael Frenneaux
Author: Joel Friedman
Author: Malte Kelm
Author: Christopher G. Kevil
Author: Daniel B. Kim-Shapiro
Author: Andrey V. Kozlov
Author: Jack R. Lancaster Jr
Author: David J. Lefer
Author: Kenneth McColl
Author: Kenneth McCurry
Author: Rakesh P. Patel
Author: Joel Petersson
Author: Tienush Rassaf
Author: Valentin P. Reutov
Author: George B. Richter-Addo
Author: Alan Schechter
Author: Sruti Shiva
Author: Koichiro Tsuchiya
Author: Ernst E. van Faassen
Author: Andrew J. Webb
Author: Brian S. Zuckerbraun
Author: Jay L. Zweier
Author: Eddie Weitzberg

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