Nitrated cyclic GMP as a new cellular signal
Feelisch, Martin (2007) Nitrated cyclic GMP as a new cellular signal. Nature Chemical Biology, 3, (11), 687-688. (doi:10.1038/nchembio1107-687). (PMID:17948012).
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Description/Abstract
Nitric oxide–mediated production of cyclic guanosine 3',5'-monophosphate (cGMP) is a crucial signal transduction pathway that controls a wide array of biological functions. A new layer of complexity in mammalian cell regulation is revealed by the discovery of a redox-active nitrated cGMP derivative with the ability to post-translationally modify protein thiol residues by S-guanylation.
| Item Type: | Article |
|---|---|
| ISSNs: | 1552-4450 (print) 1552-4469 (electronic) |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Medicine > Infection, Inflammation and Immunity |
| Item ID: | 337826 |
| Date Deposited: | 04 May 2012 12:54 |
| Last Modified: | 04 May 2012 12:54 |
| Contributors: | Feelisch, Martin (Author) |
| Date: | November 2007 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/337826 |
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