Release of endothelium derived nitric oxide in relation to pressure and flow


Kelm, Malte, Feelisch, M, Deussen, Andreas, Strauer, Bodo E. and Schrader, Jürgen (1991) Release of endothelium derived nitric oxide in relation to pressure and flow. Cardiovascular Research, 25, (10), 831-836. (doi:10.1093/cvr/25.10.831). (PMID:1747876).

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Description/Abstract

(1) The rate of NO release from endothelial cells increases when flow is enhanced. (2) Endothelial cells possess a high capacity for NO production, permitting a rapid adjustment of NO release to changes in flow. (3) The rate of NO release is not causally related to changes in perfusion pressure.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1093/cvr/25.10.831
ISSNs: 0008-6363 (print)
Related URLs:
Keywords: endothelium derived relaxing factor, nitric oxide, hypertension, thrombosis
Subjects: Q Science > QD Chemistry
R Medicine > R Medicine (General)
Divisions : Faculty of Medicine > Clinical and Experimental Sciences
ePrint ID: 337915
Accepted Date and Publication Date:
Status
October 1991Published
Date Deposited: 28 Jun 2012 15:28
Last Modified: 31 Mar 2016 14:27
URI: http://eprints.soton.ac.uk/id/eprint/337915

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