Single-center experience of catheter ablation for atrial fibrillation using multi-electrode mapping and ablation catheters


Zeb, Mehmood, Yue, Arthur M., Scott, Paul A., Roberts, Paul R. and Morgan, John M. (2011) Single-center experience of catheter ablation for atrial fibrillation using multi-electrode mapping and ablation catheters. The Journal of Invasive cardiology, 23, (10), 407-413. (PMID:21972158).

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Description/Abstract

Purpose: Radiofrequency ablation (RFA) is an established therapy for the treatment of paroxysmal and persistent atrial fibrillation (AF). Many techniques have been reported to achieve RFA. We report a single-center experience of RFA using three multi-electrode catheters.

Methods: We collected data of the patients who had RFA for AF using custom-designed multi-electrode mapping and ablation catheters between May 2007 and November 2009 at this center.

Results: A total of 105 patients aged 56 ± 9.6 years underwent RFA using three multi-electrode catheters. Eighty-seven patients were new and 18 patients had re-do AF ablation using the multi-electrode mapping and ablation catheters. In the new patients, the mean procedure duration was 141 ± 38 minutes and fluoroscopy time was 38 ± 4 minutes. The mean duration of follow-up was 15.8 ± 6.4 months. Symptomatic improvement was achieved in 75 patients (86%), 48 patients (55%) remained in sinus rhythm (SR) after the first procedure, while 7 (8%) had multiple procedures and remained in SR without antiarrhythmic drugs (AAD). Fourteen patients (16%) required AAD following a single procedure and 1 patient (1.1%) after multiple procedures to remain in SR. Seven patients (8%) had reduced burden of symptoms. No improvement occurred in 12 patients (13.7%). In the 18 re-do patients, 15 (83.3%) had symptom improvement. Four patients (22.2%) remained in SR after a single procedure and 4 patients (22.2%) required multiple procedures to remain in SR without AAD. One patient (5.5%) remained in SR on AAD following a single procedure and 1 patient (5.5%) remained in SR on AAD following multiple procedures. Five patients (27%) had reduced burden of symptoms and 3 patients (16.6%) had no improvement.

Conclusion: PVI using multi-electrode mapping and ablation catheters is an effective treatment of paroxysmal and persistent AF with a complication rate equivalent to published data.

Item Type: Article
ISSNs: 1042-3931 (print)
1557-2501 (electronic)
Related URLs:
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Human Development and Health
ePrint ID: 338789
Date Deposited: 17 May 2012 09:24
Last Modified: 27 Mar 2014 20:21
URI: http://eprints.soton.ac.uk/id/eprint/338789

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