The axillary nodal harvest in breast cancer surgery is unchanged by sentinel node biopsy or the timing of surgery

Byrne, B.E., Cutress, R.I., Gill, J., Wise, M.H., Yiangou, C. and Agrawal, A. (2012) The axillary nodal harvest in breast cancer surgery is unchanged by sentinel node biopsy or the timing of surgery. International Journal of Breast Cancer, 2012, (467825), 1-5. (doi:10.1155/2012/467825).


Full text not available from this repository.


Patients with a positive sentinel lymph node biopsy may undergo delayed completion axillary dissection. Where intraoperative analysis is available, immediate completion axillary dissection can be performed. Alternatively, patients may undergo primary axillary dissection for breast cancer, historically or when preoperative assessment suggests axillary metastases. This study aims to determine if there is a difference in the total number of lymph nodes or the number of metastatic nodes harvested between the 3 possible approaches. Methods. Three consecutive comparable groups of 50 consecutive patients who underwent axillary dissection in each of the above contexts were identified from the Portsmouth Breast Unit Database. Patient demographics, clinicopathological variables, and surgical treatment were recorded. The total pathological nodal count and the number of metastatic nodes were compared between the groups. Results. There were no differences in clinico-pathological features between the three groups for all features studied with the exception of breast surgical procedure (P<0.001). There were no differences in total nodal harvest (P=0.822) or in the number of positive nodes harvested (P=0.157) between the three groups. Conclusion. The three approaches to axillary clearance yield equivalent nodal harvests, suggesting oncological equivalence and robustness of surgical technique.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1155/2012/467825
ISSNs: 2090-3189 (print)
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions : Faculty of Medicine > Cancer Sciences
ePrint ID: 339926
Accepted Date and Publication Date:
Date Deposited: 01 Jun 2012 14:09
Last Modified: 31 Mar 2016 14:29

Actions (login required)

View Item View Item