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Fusion of enveloped virus nanoparticles with polyelectrolyte-supported lipid membranes for the design of bio/nonbio interfaces

Fusion of enveloped virus nanoparticles with polyelectrolyte-supported lipid membranes for the design of bio/nonbio interfaces
Fusion of enveloped virus nanoparticles with polyelectrolyte-supported lipid membranes for the design of bio/nonbio interfaces
Fusion of lipid-enveloped viruses with endosomal membranes triggered by low pH in the endosome is a key step in the course of viral infection. This ubiquitous mechanism can be used to integrate functional nanoparticles of viral origin into composite materials consisting of a polyelectrolyte multilayer with an adsorbed lipid membrane in a natural and biomimetic way. Polyelectrolyte multilayers as the support for the lipid membrane are a versatile means to combine the biological functions of the viral surface with the multiplicity of polyelectrolyte borne functions into a novel bio/nonbio composite material
1530-6984
3540-3546
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Reibetanz, Uta
ac641146-8f5b-46ae-8008-641b73fe72e6
Zaulig, Markus
087fd6bd-dc0c-4615-a87d-438f5d0c0b0f
Enderlein, Dirk
5822e7ff-320e-4e41-b012-ff3c702c9934
Romanova, Julia
bdbdead4-a302-4a8a-bffe-c4f5c1db1372
Leporatti, Stefano
7c08ccae-f657-4200-9ee3-cb059baff5cb
Moya, Sergio
b6034c12-474d-4a3d-a25b-9868b314ce40
Donath, Edwin
a1baee66-cc02-4a15-8c0d-732e844b8a8f
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Reibetanz, Uta
ac641146-8f5b-46ae-8008-641b73fe72e6
Zaulig, Markus
087fd6bd-dc0c-4615-a87d-438f5d0c0b0f
Enderlein, Dirk
5822e7ff-320e-4e41-b012-ff3c702c9934
Romanova, Julia
bdbdead4-a302-4a8a-bffe-c4f5c1db1372
Leporatti, Stefano
7c08ccae-f657-4200-9ee3-cb059baff5cb
Moya, Sergio
b6034c12-474d-4a3d-a25b-9868b314ce40
Donath, Edwin
a1baee66-cc02-4a15-8c0d-732e844b8a8f

Fischlechner, Martin, Reibetanz, Uta, Zaulig, Markus, Enderlein, Dirk, Romanova, Julia, Leporatti, Stefano, Moya, Sergio and Donath, Edwin (2007) Fusion of enveloped virus nanoparticles with polyelectrolyte-supported lipid membranes for the design of bio/nonbio interfaces. Nano Letters, 7 (11), 3540-3546. (doi:10.1021/nl0723580).

Record type: Article

Abstract

Fusion of lipid-enveloped viruses with endosomal membranes triggered by low pH in the endosome is a key step in the course of viral infection. This ubiquitous mechanism can be used to integrate functional nanoparticles of viral origin into composite materials consisting of a polyelectrolyte multilayer with an adsorbed lipid membrane in a natural and biomimetic way. Polyelectrolyte multilayers as the support for the lipid membrane are a versatile means to combine the biological functions of the viral surface with the multiplicity of polyelectrolyte borne functions into a novel bio/nonbio composite material

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Published date: 26 October 2007
Organisations: Organic Chemistry: SCF

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Local EPrints ID: 342562
URI: http://eprints.soton.ac.uk/id/eprint/342562
ISSN: 1530-6984
PURE UUID: 0bf7f5d2-c52f-4664-b476-e0f7383eeb11

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Date deposited: 18 Oct 2012 14:03
Last modified: 14 Mar 2024 11:52

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Contributors

Author: Martin Fischlechner
Author: Uta Reibetanz
Author: Markus Zaulig
Author: Dirk Enderlein
Author: Julia Romanova
Author: Stefano Leporatti
Author: Sergio Moya
Author: Edwin Donath

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