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Array-controlled ultrasonic manipulation of particles in planar acoustic resonator

Array-controlled ultrasonic manipulation of particles in planar acoustic resonator
Array-controlled ultrasonic manipulation of particles in planar acoustic resonator
Ultrasonic particle manipulation tools have many promising applications in life sciences, expanding on the capabilities of current manipulation technologies. In this paper, the ultrasonic manipulation of particles and cells along a microfluidic channel with a piezoelectric array is demonstrated. An array integrated into a planar multilayer resonator structure drives particles toward the pressure nodal plane along the centerline of the channel, then toward the acoustic velocity maximum centered above the subset of elements that are active. Switching the active elements along the array moves trapped particles along the microfluidic channel. A 12-element 1-D array coupled to a rectangular capillary has been modeled and fabricated for experimental testing. The device has a 300-?m-thick channel for a half-wavelength resonance near 2.5 MHz, with 500 ?m element pitch. Simulation and experiment confirm the expected trapping of particles at the center of the channel and above the set of active elements. Experiments demonstrated the feasibility of controlling the position of particles along the length of the channel by switching the active array elements.
1258-1266
Glynne-Jones, P.
6ca3fcbc-14db-4af9-83e2-cf7c8b91ef0d
Demore, C.E.M.
3fbfb94d-77cb-48a7-8fa2-cc1f2accd696
Ye, Congwei
510aa70b-f30b-4350-a921-22a842cb09a7
Qiu, Yongqiang
4f910ce0-26e4-42fb-8156-9502edbaa39d
Cochran, S.
919f7ad1-7035-4778-8124-5aef3ad5346c
Hill, M.
0cda65c8-a70f-476f-b126-d2c4460a253e
Glynne-Jones, P.
6ca3fcbc-14db-4af9-83e2-cf7c8b91ef0d
Demore, C.E.M.
3fbfb94d-77cb-48a7-8fa2-cc1f2accd696
Ye, Congwei
510aa70b-f30b-4350-a921-22a842cb09a7
Qiu, Yongqiang
4f910ce0-26e4-42fb-8156-9502edbaa39d
Cochran, S.
919f7ad1-7035-4778-8124-5aef3ad5346c
Hill, M.
0cda65c8-a70f-476f-b126-d2c4460a253e

Glynne-Jones, P., Demore, C.E.M., Ye, Congwei, Qiu, Yongqiang, Cochran, S. and Hill, M. (2012) Array-controlled ultrasonic manipulation of particles in planar acoustic resonator. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 59 (6), 1258-1266. (doi:10.1109/TUFFC.2012.2316).

Record type: Article

Abstract

Ultrasonic particle manipulation tools have many promising applications in life sciences, expanding on the capabilities of current manipulation technologies. In this paper, the ultrasonic manipulation of particles and cells along a microfluidic channel with a piezoelectric array is demonstrated. An array integrated into a planar multilayer resonator structure drives particles toward the pressure nodal plane along the centerline of the channel, then toward the acoustic velocity maximum centered above the subset of elements that are active. Switching the active elements along the array moves trapped particles along the microfluidic channel. A 12-element 1-D array coupled to a rectangular capillary has been modeled and fabricated for experimental testing. The device has a 300-?m-thick channel for a half-wavelength resonance near 2.5 MHz, with 500 ?m element pitch. Simulation and experiment confirm the expected trapping of particles at the center of the channel and above the set of active elements. Experiments demonstrated the feasibility of controlling the position of particles along the length of the channel by switching the active array elements.

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Published date: June 2012
Organisations: Mechatronics

Identifiers

Local EPrints ID: 343248
URI: http://eprints.soton.ac.uk/id/eprint/343248
PURE UUID: ee81eef3-bab0-487b-b2c1-cfc0a1e69ed2
ORCID for P. Glynne-Jones: ORCID iD orcid.org/0000-0001-5684-3953
ORCID for M. Hill: ORCID iD orcid.org/0000-0001-6448-9448

Catalogue record

Date deposited: 01 Oct 2012 11:30
Last modified: 15 Mar 2024 03:03

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Contributors

Author: P. Glynne-Jones ORCID iD
Author: C.E.M. Demore
Author: Congwei Ye
Author: Yongqiang Qiu
Author: S. Cochran
Author: M. Hill ORCID iD

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