Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor
Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor
The effects of osmotic pressure and dilution rate were investigated on the continuous production of glycerol in a multistage cascade bioreactor. The results showed that high osmotic pressure could improve fermentation performance significantly. At a dilution rate of 0.050 h?1 and feeding 400 g l?1 glucose solution, a glycerol yield of 25.0% based on glucose consumed and a maximum productivity of 19.4 g l?1 per day were obtained, respectively, in a six-stage cascade bioreactor. When the dilution rate was increased from 0.023 to 0.085 h?1, the glycerol yield, based on biomass, remained constant, but specific productivity increased by 94.7%. Productivity increased by only 46.6% due to low biomass concentration in the bioreactor at the higher dilution rates.
multistage cascade bioreactor, osmophilic yeast, osmotic pressure, dilution rate, glycerol
427-432
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Liu, Jingrui
d1415294-49cc-49ce-b554-d9ad4619f7c6
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63
2002
Liu, Yongqiang
75adc6f8-aa83-484e-9e87-6c8442e344fa
Liu, Dehua
2f9ded17-8371-46cf-98f1-803c92360d06
Su, Qiong
462fab98-be91-49c0-a37c-22d35736cc9b
Liu, Jingrui
d1415294-49cc-49ce-b554-d9ad4619f7c6
Xie, Dongming
9d651a52-0d08-4936-9746-128aa52c9b63
Liu, Yongqiang, Liu, Dehua, Su, Qiong, Liu, Jingrui and Xie, Dongming
(2002)
Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor.
Process Biochemistry, 38 (3), .
(doi:10.1016/S0032-9592(02)00149-8).
Abstract
The effects of osmotic pressure and dilution rate were investigated on the continuous production of glycerol in a multistage cascade bioreactor. The results showed that high osmotic pressure could improve fermentation performance significantly. At a dilution rate of 0.050 h?1 and feeding 400 g l?1 glucose solution, a glycerol yield of 25.0% based on glucose consumed and a maximum productivity of 19.4 g l?1 per day were obtained, respectively, in a six-stage cascade bioreactor. When the dilution rate was increased from 0.023 to 0.085 h?1, the glycerol yield, based on biomass, remained constant, but specific productivity increased by 94.7%. Productivity increased by only 46.6% due to low biomass concentration in the bioreactor at the higher dilution rates.
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Published date: 2002
Keywords:
multistage cascade bioreactor, osmophilic yeast, osmotic pressure, dilution rate, glycerol
Organisations:
Water & Environmental Engineering Group
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Local EPrints ID: 352845
URI: http://eprints.soton.ac.uk/id/eprint/352845
ISSN: 1359-5113
PURE UUID: 4f6e20b7-d864-407d-bbb4-af7b852d7370
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Date deposited: 17 Jun 2013 15:24
Last modified: 15 Mar 2024 03:47
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Author:
Dehua Liu
Author:
Qiong Su
Author:
Jingrui Liu
Author:
Dongming Xie
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