Ultrasound assisted particle and cell manipulation on-chip
Ultrasound assisted particle and cell manipulation on-chip
Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ability to handle many cells simultaneously over extended length scales. This paper provides an overview of the physical principles underlying ultrasonic manipulation, discusses the biological effects relevant to its use with cells, and describes emerging applications that are of interest in the field of drug development and delivery on-chip.
acoustofluidics, ultrasonic radiation forces, microfluidics, lab-on-chip, acoustic streaming
1600-1610
Mulvana, Helen
8d883285-1b24-43ba-aa1b-a5df89ea86e6
Cochran, Sandy
9002d992-d724-4912-ac1c-ec9e82cfe9ed
Hill, Martyn
0cda65c8-a70f-476f-b126-d2c4460a253e
15 November 2013
Mulvana, Helen
8d883285-1b24-43ba-aa1b-a5df89ea86e6
Cochran, Sandy
9002d992-d724-4912-ac1c-ec9e82cfe9ed
Hill, Martyn
0cda65c8-a70f-476f-b126-d2c4460a253e
Mulvana, Helen, Cochran, Sandy and Hill, Martyn
(2013)
Ultrasound assisted particle and cell manipulation on-chip.
[in special issue: Design Production and Characterization of Drug Delivery Systems by Lab-on-a-Chip Technology]
Advanced Drug Delivery Reviews, 65 (11-12), .
(doi:10.1016/j.addr.2013.07.016).
Abstract
Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing lab-on-chip techniques and is complementary to many alternative manipulation approaches due to its ability to handle many cells simultaneously over extended length scales. This paper provides an overview of the physical principles underlying ultrasonic manipulation, discusses the biological effects relevant to its use with cells, and describes emerging applications that are of interest in the field of drug development and delivery on-chip.
Text
Ultrasonic manipulation on chip.pdf
- Accepted Manuscript
More information
e-pub ahead of print date: 29 July 2013
Published date: 15 November 2013
Keywords:
acoustofluidics, ultrasonic radiation forces, microfluidics, lab-on-chip, acoustic streaming
Organisations:
Mechatronics
Identifiers
Local EPrints ID: 355198
URI: http://eprints.soton.ac.uk/id/eprint/355198
ISSN: 0169-409X
PURE UUID: ce4e2c3c-90fb-4435-ba46-b8a757da37b4
Catalogue record
Date deposited: 13 Aug 2013 16:03
Last modified: 15 Mar 2024 02:42
Export record
Altmetrics
Contributors
Author:
Helen Mulvana
Author:
Sandy Cochran
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
