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Takotsubo cardiomyopathy: a diagnostic challenge

Takotsubo cardiomyopathy: a diagnostic challenge
Takotsubo cardiomyopathy: a diagnostic challenge
The frequency of the diagnosis of takotsubo cardiomyopathy has increased rapidly over the past few years, possibly due to increasing awareness among cardiologists. At initial presentation the diagnosis remains a challenge because of the close similarity between the presentation of takotsubo cardiomyopathy, and that of ST elevation myocardial infarction (STEMI). Recognition of salient aspects of the medical history at presentation are important in order to organise further appropriate investigations such as echocardiography and left ventriculography at the time of coronary angiogram. Takotsubo cardiomyopathy can be easily missed without ventriculography early after presentation because of the transient nature of left ventricular dysfunction, and in many centres left ventriculogram is not done as standard in the setting of STEMI. The authors advocate left ventriculography in all cases of ST elevation who have unobstructed coronaries. The correct diagnosis of takotsubo cardiomyopathy is very important for future advice and management of the patient. The prognosis of this condition is generally excellent with almost all patients returning to normal within a few weeks. This article examines the takotsubo cardiomyopathy literature and discusses the pathophysiology, clinical features, management, and prognosis of this condition in the context of an illustrated case.
0032-5473
51-59
Zeb, Mehmood
469fda8e-8318-4fe5-97f3-a46eec60f333
Sambu, Nalyaka
7d0ba3fb-e39e-48d7-a0e4-ce249acc5980
Scott, Paul A.
5a16b1f4-74d3-473f-9eeb-c2a823d690dc
Curzen, N.
70f3ea49-51b1-418f-8e56-8210aef1abf4
Zeb, Mehmood
469fda8e-8318-4fe5-97f3-a46eec60f333
Sambu, Nalyaka
7d0ba3fb-e39e-48d7-a0e4-ce249acc5980
Scott, Paul A.
5a16b1f4-74d3-473f-9eeb-c2a823d690dc
Curzen, N.
70f3ea49-51b1-418f-8e56-8210aef1abf4

Zeb, Mehmood, Sambu, Nalyaka, Scott, Paul A. and Curzen, N. (2011) Takotsubo cardiomyopathy: a diagnostic challenge. Postgraduate Medical Journal, 87 (1023), 51-59. (doi:10.1136/pgmj.2010.102475). (PMID:21059600)

Record type: Article

Abstract

The frequency of the diagnosis of takotsubo cardiomyopathy has increased rapidly over the past few years, possibly due to increasing awareness among cardiologists. At initial presentation the diagnosis remains a challenge because of the close similarity between the presentation of takotsubo cardiomyopathy, and that of ST elevation myocardial infarction (STEMI). Recognition of salient aspects of the medical history at presentation are important in order to organise further appropriate investigations such as echocardiography and left ventriculography at the time of coronary angiogram. Takotsubo cardiomyopathy can be easily missed without ventriculography early after presentation because of the transient nature of left ventricular dysfunction, and in many centres left ventriculogram is not done as standard in the setting of STEMI. The authors advocate left ventriculography in all cases of ST elevation who have unobstructed coronaries. The correct diagnosis of takotsubo cardiomyopathy is very important for future advice and management of the patient. The prognosis of this condition is generally excellent with almost all patients returning to normal within a few weeks. This article examines the takotsubo cardiomyopathy literature and discusses the pathophysiology, clinical features, management, and prognosis of this condition in the context of an illustrated case.

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More information

e-pub ahead of print date: 7 November 2010
Published date: January 2011
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 355227
URI: http://eprints.soton.ac.uk/id/eprint/355227
ISSN: 0032-5473
PURE UUID: 7b74bf90-c692-4792-925b-f8f99796d475
ORCID for N. Curzen: ORCID iD orcid.org/0000-0001-9651-7829

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Date deposited: 13 Aug 2013 14:56
Last modified: 15 Mar 2024 03:23

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Contributors

Author: Mehmood Zeb
Author: Nalyaka Sambu
Author: Paul A. Scott
Author: N. Curzen ORCID iD

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