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A closed-loop control strategy for glucose control in artificial pancreas systems

A closed-loop control strategy for glucose control in artificial pancreas systems
A closed-loop control strategy for glucose control in artificial pancreas systems
Maintaining good glycemic control is a continuous challenge for type-1 diabetic patients. The current means of insulin therapy are seen to subject patients to hyper- and hypoglycemic episodes. With the advancement of computer science and technology, an artificial pancreas; a computerized device that will automatically control patient’s blood glucose level by providing the substitute for the insulin supply functionality of a healthy pancreas was proposed. The main challenge faced by the development of this device is a fully closed-loop control system. In this paper we proposed an artificial pancreas system with an adaptive closed-loop control strategy that computes the appropriate insulin infusion rate and thereby keeping the patient’s blood glucose concentration within normoglycemic range. The adaptability is achieved through a rigorous pattern recognition technique with patient-specific glucose readings obtained through glucose monitor at a given sampling step. The performance of the control strategy is assessed using the simulation results carried out under various physiological disturbances and meal intake.
type-1 diabetes, artificial pancreas, computerizedclosed-loop control system, pattern recognition technique
978-1-4673-4704-4
295-299
Galadanci, Jamil
92fa1565-de7f-439f-b898-14d1dbb35ebd
Shafik, Rishad Ahmed
aa0bdafc-b022-4cb2-a8ef-4bf8a03ba524
Mathew, Jimson
156eec1e-d690-43eb-a72f-daefd8b04144
Acharyya, Amit
f7c95a87-04ac-4d13-a74c-0c4d89b1c79c
Pradhan, Dhiraj K.
14f13d30-42ec-43bf-941b-3116a7f803fc
Galadanci, Jamil
92fa1565-de7f-439f-b898-14d1dbb35ebd
Shafik, Rishad Ahmed
aa0bdafc-b022-4cb2-a8ef-4bf8a03ba524
Mathew, Jimson
156eec1e-d690-43eb-a72f-daefd8b04144
Acharyya, Amit
f7c95a87-04ac-4d13-a74c-0c4d89b1c79c
Pradhan, Dhiraj K.
14f13d30-42ec-43bf-941b-3116a7f803fc

Galadanci, Jamil, Shafik, Rishad Ahmed, Mathew, Jimson, Acharyya, Amit and Pradhan, Dhiraj K. (2012) A closed-loop control strategy for glucose control in artificial pancreas systems. ISED 2012: International Symposium on Electronic Systems Design, Kolkata, India. 19 - 22 Dec 2012. pp. 295-299 . (doi:10.1109/ISED.2012.76).

Record type: Conference or Workshop Item (Paper)

Abstract

Maintaining good glycemic control is a continuous challenge for type-1 diabetic patients. The current means of insulin therapy are seen to subject patients to hyper- and hypoglycemic episodes. With the advancement of computer science and technology, an artificial pancreas; a computerized device that will automatically control patient’s blood glucose level by providing the substitute for the insulin supply functionality of a healthy pancreas was proposed. The main challenge faced by the development of this device is a fully closed-loop control system. In this paper we proposed an artificial pancreas system with an adaptive closed-loop control strategy that computes the appropriate insulin infusion rate and thereby keeping the patient’s blood glucose concentration within normoglycemic range. The adaptability is achieved through a rigorous pattern recognition technique with patient-specific glucose readings obtained through glucose monitor at a given sampling step. The performance of the control strategy is assessed using the simulation results carried out under various physiological disturbances and meal intake.

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More information

Published date: 19 December 2012
Venue - Dates: ISED 2012: International Symposium on Electronic Systems Design, Kolkata, India, 2012-12-19 - 2012-12-22
Keywords: type-1 diabetes, artificial pancreas, computerizedclosed-loop control system, pattern recognition technique
Organisations: Electronic & Software Systems

Identifiers

Local EPrints ID: 355293
URI: http://eprints.soton.ac.uk/id/eprint/355293
ISBN: 978-1-4673-4704-4
PURE UUID: d8e801aa-4d55-415b-9617-e4f4529cd04b

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Date deposited: 28 Aug 2013 11:00
Last modified: 14 Mar 2024 14:31

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Contributors

Author: Jamil Galadanci
Author: Rishad Ahmed Shafik
Author: Jimson Mathew
Author: Amit Acharyya
Author: Dhiraj K. Pradhan

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