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Photodynamic therapy for retinal capillary hemangioma

Photodynamic therapy for retinal capillary hemangioma
Photodynamic therapy for retinal capillary hemangioma
PURPOSE: To describe the results of photodynamic therapy (PDT) for juxtapapillary and peripheral retinal capillary hemangioma (RCH).

PATIENTS AND METHODS: Interventional case series of four eyes (four patients) with juxtapapillary RCH and one eye (one patient) with peripheral RCH. Two eyes with juxtapapillary RCH had received two sessions of full-fluence, double-duration PDT; whereas other two eyes had received single session of half-fluence, single-duration PDT. The peripheral RCH was treated with a single session of full-fluence, single-duration PDT.

RESULTS: Two patients had von Hippel-Lindau disease. Follow-up duration ranged from 4 months to 1 year. Pre-PDT visual acuity (VA) ranged from 20/200 to HM (juxtapapillary RCH) and 20/100 (peripheral RCH). Among the eyes with juxtapapillary RCH, tumor regression with partial resolution of macular edema was noted in two eyes (one eye each with half-fluence and full-fluence PDT), whereas two eyes had no change in tumor size with persistent macular edema. VA remained stable in three eyes and declined in one eye. In an eye with peripheral RCH, regression of tumor and macular edema with VA improvement was noted. Post-PDT complications included epiretinal membrane (one eye) and transient exudative retinal detachment (one eye).

CONCLUSION: PDT can be effective in reducing macular edema associated with RCH but this does not always correspond with an improvement in VA especially for juxtapapillary tumors.
0950-222X
438-442
Papastefanou, V.P.
75b962fa-fbc0-473b-8446-d0648c4af957
Pilli, S.
854b0cd2-2272-42c0-b27e-48cb63bd3efe
Stinghe, A.
1198d728-1409-4d5d-be09-1193fa598371
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Cohen, V.M.L.
bd9e0bc7-b3fd-4f7c-8e4c-653a374aa2c0
Papastefanou, V.P.
75b962fa-fbc0-473b-8446-d0648c4af957
Pilli, S.
854b0cd2-2272-42c0-b27e-48cb63bd3efe
Stinghe, A.
1198d728-1409-4d5d-be09-1193fa598371
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Cohen, V.M.L.
bd9e0bc7-b3fd-4f7c-8e4c-653a374aa2c0

Papastefanou, V.P., Pilli, S., Stinghe, A., Lotery, A.J. and Cohen, V.M.L. (2013) Photodynamic therapy for retinal capillary hemangioma. Eye, 27 (3), 438-442. (doi:10.1038/eye.2012.259). (PMID:23288135)

Record type: Article

Abstract

PURPOSE: To describe the results of photodynamic therapy (PDT) for juxtapapillary and peripheral retinal capillary hemangioma (RCH).

PATIENTS AND METHODS: Interventional case series of four eyes (four patients) with juxtapapillary RCH and one eye (one patient) with peripheral RCH. Two eyes with juxtapapillary RCH had received two sessions of full-fluence, double-duration PDT; whereas other two eyes had received single session of half-fluence, single-duration PDT. The peripheral RCH was treated with a single session of full-fluence, single-duration PDT.

RESULTS: Two patients had von Hippel-Lindau disease. Follow-up duration ranged from 4 months to 1 year. Pre-PDT visual acuity (VA) ranged from 20/200 to HM (juxtapapillary RCH) and 20/100 (peripheral RCH). Among the eyes with juxtapapillary RCH, tumor regression with partial resolution of macular edema was noted in two eyes (one eye each with half-fluence and full-fluence PDT), whereas two eyes had no change in tumor size with persistent macular edema. VA remained stable in three eyes and declined in one eye. In an eye with peripheral RCH, regression of tumor and macular edema with VA improvement was noted. Post-PDT complications included epiretinal membrane (one eye) and transient exudative retinal detachment (one eye).

CONCLUSION: PDT can be effective in reducing macular edema associated with RCH but this does not always correspond with an improvement in VA especially for juxtapapillary tumors.

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More information

Published date: 4 January 2013
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 359167
URI: http://eprints.soton.ac.uk/id/eprint/359167
ISSN: 0950-222X
PURE UUID: 1ea094f2-c440-496d-8cd6-45227166f71f
ORCID for A.J. Lotery: ORCID iD orcid.org/0000-0001-5541-4305

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Date deposited: 23 Oct 2013 12:39
Last modified: 15 Mar 2024 03:16

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Contributors

Author: V.P. Papastefanou
Author: S. Pilli
Author: A. Stinghe
Author: A.J. Lotery ORCID iD
Author: V.M.L. Cohen

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