Electrophysiology findings in a large family with central areolar choroidal dystrophy
Electrophysiology findings in a large family with central areolar choroidal dystrophy
All affected, but clinically normal, youngest generation patients had bilaterally abnormal PVEPs and PERGs. In CACD the PVEP and PERG proved to be the most sensitive electrophysiological tests of preclincial macular dysfunction, 3/3 subjects abnormal. ERG recording to ISCEV guidelines were very useful in these cases; 7/8 subjects abnormal. The EOG was less useful; 4/8 subjects abnormal. CACD produces a widespread photoreceptor dysfunction in its later stages.
central areolar choroidal dystrophy, chromosome 17p, electrophysiology, electroretinogram, visual evoked potential
103-119
Lotery, A J
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Silvestri, G
2a2ceb40-4464-4a87-b033-0cb6a0dcfc74
Collins, A D
7278ad0f-4ac4-4196-bf73-516bbab7d584
1998
Lotery, A J
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Silvestri, G
2a2ceb40-4464-4a87-b033-0cb6a0dcfc74
Collins, A D
7278ad0f-4ac4-4196-bf73-516bbab7d584
Lotery, A J, Silvestri, G and Collins, A D
(1998)
Electrophysiology findings in a large family with central areolar choroidal dystrophy.
Documenta Ophthalmologica, 97 (2), .
(PMID:10765965)
Abstract
All affected, but clinically normal, youngest generation patients had bilaterally abnormal PVEPs and PERGs. In CACD the PVEP and PERG proved to be the most sensitive electrophysiological tests of preclincial macular dysfunction, 3/3 subjects abnormal. ERG recording to ISCEV guidelines were very useful in these cases; 7/8 subjects abnormal. The EOG was less useful; 4/8 subjects abnormal. CACD produces a widespread photoreceptor dysfunction in its later stages.
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Published date: 1998
Keywords:
central areolar choroidal dystrophy, chromosome 17p, electrophysiology, electroretinogram, visual evoked potential
Organisations:
Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 359194
URI: http://eprints.soton.ac.uk/id/eprint/359194
ISSN: 0012-4486
PURE UUID: e5a49065-cd02-4634-91ae-6dbbbd5b4e40
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Date deposited: 01 Nov 2013 15:57
Last modified: 08 Jan 2022 02:58
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Author:
G Silvestri
Author:
A D Collins
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