Construction of DNA–polymer hybrids using intercalation interactions
Construction of DNA–polymer hybrids using intercalation interactions
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy
1338-1340
Wilks, Thomas R.
f3e9f3ae-6f93-4a1b-89a0-6916e353aa24
Pitto-Barry, Anaïs
5ee2b8c8-34ec-4ac4-bceb-9ccc29063344
Kirby, Nigel
f096d265-c00e-42e0-8cd8-fb5ab470f513
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
O'Reilly, Rachel K.
086bc91e-2303-4543-b79c-ae16ada0b101
2014
Wilks, Thomas R.
f3e9f3ae-6f93-4a1b-89a0-6916e353aa24
Pitto-Barry, Anaïs
5ee2b8c8-34ec-4ac4-bceb-9ccc29063344
Kirby, Nigel
f096d265-c00e-42e0-8cd8-fb5ab470f513
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
O'Reilly, Rachel K.
086bc91e-2303-4543-b79c-ae16ada0b101
Wilks, Thomas R., Pitto-Barry, Anaïs, Kirby, Nigel, Stulz, Eugen and O'Reilly, Rachel K.
(2014)
Construction of DNA–polymer hybrids using intercalation interactions.
Chemical Communications, 50, .
(doi:10.1039/C3CC48726A).
Abstract
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy
This record has no associated files available for download.
More information
Published date: 2014
Organisations:
Chemistry
Identifiers
Local EPrints ID: 361088
URI: http://eprints.soton.ac.uk/id/eprint/361088
ISSN: 1359-7345
PURE UUID: 1b9a91a2-6ab5-4466-bea0-38565aa505c4
Catalogue record
Date deposited: 13 Jan 2014 13:25
Last modified: 15 Mar 2024 03:26
Export record
Altmetrics
Contributors
Author:
Thomas R. Wilks
Author:
Anaïs Pitto-Barry
Author:
Nigel Kirby
Author:
Rachel K. O'Reilly
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
