Tumour grade on core biopsy and evidence of axillary involvement on ultrasound predicts response in elderly co-morbid patients treated with primary hormone therapy for oestrogen receptor positive breast carcinoma
Tumour grade on core biopsy and evidence of axillary involvement on ultrasound predicts response in elderly co-morbid patients treated with primary hormone therapy for oestrogen receptor positive breast carcinoma
A high proportion of elderly and comorbid patients die with breast cancer rather than from breast cancer. Elderly comorbid patients who initially respond to primary hormone therapy have a less than 30% incidence of delayed treatment failure during their life time; however patients with grade III disease or an abnormal axillary ultrasound are twice as likely to fail first choice PHT.
Layfield, D.M.
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Mohamud, C.
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Odofin, O.
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Walshe, Claire A.
dc2839de-0958-478e-a3fe-e7ed361fcda2
Royle, G.T.
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Cutress, R.I.
68ae4f86-e8cf-411f-a335-cdba51797406
8 January 2014
Layfield, D.M.
3f5ffdd6-6ec0-43dd-95a8-5752bcefe7f5
Mohamud, C.
6ef76735-157f-4d2b-a65b-2b57c9f52f24
Odofin, O.
b2c8fe1f-99da-4b45-9cd6-c52e6e2a94d2
Walshe, Claire A.
dc2839de-0958-478e-a3fe-e7ed361fcda2
Royle, G.T.
e69d4bfe-16df-454d-9b69-1230054b8120
Cutress, R.I.
68ae4f86-e8cf-411f-a335-cdba51797406
Layfield, D.M., Mohamud, C., Odofin, O., Walshe, Claire A., Royle, G.T. and Cutress, R.I.
(2014)
Tumour grade on core biopsy and evidence of axillary involvement on ultrasound predicts response in elderly co-morbid patients treated with primary hormone therapy for oestrogen receptor positive breast carcinoma.
The Surgeon.
(doi:10.1016/j.surge.2013.11.021).
(PMID:24411703)
Abstract
A high proportion of elderly and comorbid patients die with breast cancer rather than from breast cancer. Elderly comorbid patients who initially respond to primary hormone therapy have a less than 30% incidence of delayed treatment failure during their life time; however patients with grade III disease or an abnormal axillary ultrasound are twice as likely to fail first choice PHT.
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Published date: 8 January 2014
Organisations:
Cancer Sciences
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Local EPrints ID: 368062
URI: http://eprints.soton.ac.uk/id/eprint/368062
ISSN: 1479-666X
PURE UUID: 7d47cbd0-b306-4187-b9f0-db095dd50a86
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Date deposited: 29 Aug 2014 11:03
Last modified: 14 Mar 2024 17:41
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Contributors
Author:
D.M. Layfield
Author:
C. Mohamud
Author:
O. Odofin
Author:
Claire A. Walshe
Author:
G.T. Royle
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