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Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials

Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials
Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials
In this study one half of respiratory serious adverse events were attributed to definite or suspected acute exacerbations. Suspected acute exacerbations are clinically indistinguishable from definite acute exacerbations and represent clinically meaningful events. Clinical trialists should consider capturing both definite and suspected acute exacerbations as outcome measures.
1465-9921
73
Collard, Harold R.
6eee2ce5-3016-4c13-ac58-f30a77f7d141
Yow, Eric
b949a7a6-5900-49b6-aebb-0b5f9d0f13b9
Richeldi, Luca
47177d9c-731a-49a1-9cc6-4ac8f6bbbf26
Anstrom, Kevin J.
a0075b1b-d45a-41ed-9c9c-2f7fbdaeaed3
Glazer, Craig
e4a4c022-847b-4b70-8877-ae8cf2b035ad
Collard, Harold R.
6eee2ce5-3016-4c13-ac58-f30a77f7d141
Yow, Eric
b949a7a6-5900-49b6-aebb-0b5f9d0f13b9
Richeldi, Luca
47177d9c-731a-49a1-9cc6-4ac8f6bbbf26
Anstrom, Kevin J.
a0075b1b-d45a-41ed-9c9c-2f7fbdaeaed3
Glazer, Craig
e4a4c022-847b-4b70-8877-ae8cf2b035ad

Collard, Harold R., Yow, Eric, Richeldi, Luca, Anstrom, Kevin J. and Glazer, Craig (2013) Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials. Respiratory Research, 14, 73. (doi:10.1186/1465-9921-14-73). (PMID:23848435)

Record type: Article

Abstract

In this study one half of respiratory serious adverse events were attributed to definite or suspected acute exacerbations. Suspected acute exacerbations are clinically indistinguishable from definite acute exacerbations and represent clinically meaningful events. Clinical trialists should consider capturing both definite and suspected acute exacerbations as outcome measures.

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Published date: July 2013
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 369044
URI: http://eprints.soton.ac.uk/id/eprint/369044
ISSN: 1465-9921
PURE UUID: 6f18948d-af05-4779-a440-06463b695876

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Date deposited: 24 Sep 2014 10:42
Last modified: 14 Mar 2024 17:57

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Contributors

Author: Harold R. Collard
Author: Eric Yow
Author: Luca Richeldi
Author: Kevin J. Anstrom
Author: Craig Glazer

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