The University of Southampton
University of Southampton Institutional Repository

Anion transport across varying lipid membranes – the effect of lipophilicity

Anion transport across varying lipid membranes – the effect of lipophilicity
Anion transport across varying lipid membranes – the effect of lipophilicity
The anion transport properties of a range of alkyl-substituted phenylthioureas were tested in vesicles of different lipid composition. Although changes in the bilayer affected the rate of transport for all compounds in the series, the ‘ideal’ log P for peak activity did not change depending on the composition of the bilayers tested.
1359-7345
4883-4886
Spooner, Michael J.
b2fc20ec-22e1-42f9-82b8-5afd2666c25d
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943
Spooner, Michael J.
b2fc20ec-22e1-42f9-82b8-5afd2666c25d
Gale, Philip A.
c840b7e9-6847-4843-91af-fa0f8563d943

Spooner, Michael J. and Gale, Philip A. (2015) Anion transport across varying lipid membranes – the effect of lipophilicity. Chemical Communications, 51, 4883-4886. (doi:10.1039/c5cc00823a).

Record type: Article

Abstract

The anion transport properties of a range of alkyl-substituted phenylthioureas were tested in vesicles of different lipid composition. Although changes in the bilayer affected the rate of transport for all compounds in the series, the ‘ideal’ log P for peak activity did not change depending on the composition of the bilayers tested.

Text
Lip Series ChemComm 12.pdf - Accepted Manuscript
Download (1MB)
Spreadsheet
Titration Data.xlsx - Other
Download (65kB)
Archive
Vesicle Data.zip - Other
Download (11MB)
Text
c5cc00823a.pdf - Version of Record
Available under License Other.
Download (1MB)

More information

Accepted/In Press date: 13 February 2015
e-pub ahead of print date: 23 February 2015
Organisations: Organic Chemistry: SCF

Identifiers

Local EPrints ID: 374621
URI: http://eprints.soton.ac.uk/id/eprint/374621
ISSN: 1359-7345
PURE UUID: 612dc18d-d745-440d-bda7-d55bfd67a4ff
ORCID for Philip A. Gale: ORCID iD orcid.org/0000-0001-9751-4910

Catalogue record

Date deposited: 24 Feb 2015 14:36
Last modified: 15 Mar 2024 03:06

Export record

Altmetrics

Contributors

Author: Michael J. Spooner
Author: Philip A. Gale ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×